Exploring the association of Bone Alkaline Phosphatases And Hearing Loss

Abstract

Hearing loss becomes increasingly common with age and affects quality of life. Recently, scientists have published articles about the relationship between metabolic disease and hearing loss. Metabolic disease was previously found to be highly related to an increase in alkaline phosphatase. Thus, there may be an indirect relationship between alkaline phosphatase (ALP) and hearing loss. In this paper, we will demonstrate the relationship between ALP and hearing loss. We included 3877 National Health and Nutrition Examination Survey (NHANES) participants, who represent the noninstitutionalized civilian population in the United States from age 20 to age 69, and examined the association between ALP and frequency distributions of pure-tone air-condition (PTAC) thresholds. After adjusting for pertinent variables, the subjects who belonged to the higher quartiles of ALP tended to have worse hearing thresholds (pure tone average at high and low frequencies) than the first quartile of ALP (p < 0.001). The results showed a positive correlation between ALP and hearing loss, in both males and females (p < 0.001) and in subjects whose body mass indices (BMI) were less than 30 (p < 0.001). In conclusion, ALP may play a role in detecting hearing loss.

Organic–inorganic hybrid [NH3(CH2)6NH3]ZnBr4 crystal: structural characterization, phase transitions, thermal properties, and structural dynamics

“…The molecular weight loss began at approximately 600 K, which was defined as the partial thermal decomposition temperature, T d , where at 5% weight loss occurred. From the total molecular weight of 503.23 mg, the residual amounts after the decomposition of HBr and 2HBr were calculated using eqn (1) and (2), respectively: 33 {[NH 2 (CH 2 ) 6 NH 2 ·HBr]ZnBr 3 + HBr (g)}/[NH 3 (CH 2 ) 6 NH 3 ]ZnBr 4 = 92.75%{[NH 2 (CH 2 ) 6 NH 2 ]ZnBr 2 + 2HBr (g)}/[NH 3 (CH 2 ) 6 NH 3 ]ZnBr 4 = 85.51%…”

“…14 N has a spin number of 1, and two resonance signals are expected by the quadrupole interaction. 33 The 14 N resonance frequency was very low at 28.90 MHz, and it was not easy to obtain a resonance signal by wiggling of the base line. However, because the intensity was small and the line width was relatively broad, it was difficult to distinguish the signals (inset of Fig.…”

“…The spin–lattice relaxation time, T 1ρ , values were obtained using a π/2– τ pulse, followed by a spin-lock pulse of duration τ , and the π/2 pulse widths for 1 H and 13 C were measured by a previously published method. 33 Static 14 N NMR resonance frequencies were recorded with a Larmor frequency of ω o /2π = 28.90 MHz using the one-pulse method and NH 4 NO 3 was used as the reference material. The temperature during the NMR experiment ranged from 180 to 430 K; owing to the limitations of the instrument, measurements at higher temperatures were not possible.…”

Phase transition, thermal stability, and molecular dynamics of organic–inorganic hybrid perovskite [NH3(CH2)6NH3]CuCl4 crystals

“…The T 1r values were obtained from the spectra measured using a p/2Às pulse followed by a spin-lock pulse of duration s, and the p/2 pulse widths for 1 H and 13 C were measured using the method described here. 36…”

Exploring the association of organochlorine pesticides exposure and hearing impairment in United States adults

“…The detailed procedure and protocol of audiometric examination have been described in the NHANES audiometry procedures online manual 26 and previous papers 27 , 28 . Briefly, half of the sample of US adults aged 20–69 years underwent an audiometric component test.…”