Exploring interaction dynamics of designed organic cocrystal charge transfer complex of 2-hydroxypyridine and oxalic acid with human serum albumin: Single crystal, spectrophotometric, theoretical and antimicrobial studies

Rational synthesis of IR820–albumin complex for NIR-II fluorescence imaging-guided surgical treatment of tumors and gastrointestinal obstruction

“…S3 † ). 66 In addition, a fluorescence titration experiment was performed by gradually adding IR820 into HSA to quench the fluorescence of HSA at 330 nm. The calculated binding constants determined by the Stern–Volmer equation were all above 1 × 10 5 L mol −1 , which indicated that IR820 had an excellent affinity to HSA under acidic and physiological conditions (Fig.…”

Exploring the charge transfer dynamics of hydrogen bonded crystals of 2-methyl-8-quinolinol and chloranilic acid: synthesis, spectrophotometric, single-crystal, DFT/PCM analysis, antimicrobial, and DNA binding studies

“…The antifungal activity was tested against three different fungal strains, and clindamycin was used as a standard drug. 31 A concentration of 1 mg mL −1 of CT complex was treated against Fusarium oxysporum , Sclerotium rolfsii , and Phytophthora strains, and the result of the HB CT complex on the growth of fungal strains is depicted in Fig. S7.…”

“…CT complexes may play a signicant role in antimicrobial and DNA binding studies. 25,[31][32][33][34] Based on the preceding discussion, and owing to the importance of 2 MQ from a chemistry point of view and to the wide range of biological activities and pharmacological applications of 2 MQ, this work focuses on exploring antimicrobial and DNA binding studies. The experimental work will take in the use of different spectroscopic techniques such as UV-vis, FT-IR, 1 H and 13 C NMR spectroscopies; SEM-EDX; single-crystal X-ray diffraction (XRD); powder XRD; and TGA-DTA analysis to characterize the produced HB CT complex in different solvents: ACN, MeOH, and EtOH.…”

Increasing the Efficacy of Seproxetine as an Antidepressant Using Charge–Transfer Complexes

“…Charge–transfer (CT) complexation, or electron–donor transfer, is a crucial aspect of biochemical and biological processes such as drug design, enzyme catalysis, and ion sensing [ 9 ]. The pharmacodynamics and thermodynamics of therapeutic substances and biological processes in the human body are studied using charge–transfer complexation interactions [ 10 , 11 , 12 , 13 , 14 ]. In biological systems, charge–transfer complexes may play a crucial function.…”