Ergonomics awareness substantially affects the business, association, administration, workers and general prosperity of the framework. Since there exist a very limited study on the issue of ergomomic awareness, this paper aim at investigating ergonomic awareness and its effect on safety culture.Questionaires were distributed to employees from manufacturing company in Pahang, Negeri Sembilan and Terengganu. A total of 300 questionaires were distributed but only 200 questionares were return and usable represent 67% of respond rate. Data analysis used IBM Statistical Packages for the Social Science (SPSS) version 22, and Partial Least Square Structural Equation Model (PLS-SEM) version 3.0. Finding of the study revealed that all factor loadings and average variance extracted (AVE) surpassed the prescribed estimation of 0.5 and AVE construct range from 0.960 to 0.983 which surpassed the suggested estimation of 0.7. All the hypothesis of this investigation is bolstered and acknowledged. It was discovered that usage and change were the most critical indicator of the degree of ergonomic awareness took after by supportability of occupation. The higher the degree of ergonomic awareness, the better is the firm's safety culture.