Exploration of industrially important pigments from soil fungi

Akilandeswari, P.; Pradeep, B. V.

doi:10.1007/s00253-015-7231-8

Cited by 82 publications

(56 citation statements)

References 81 publications

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“…In order to improve performance and reduce the cost of pigments produced by microbial fermentation, it is essential to identify the nutritional and physical factors that have a greater influence on the cell growth and metabolite biosynthesis [4,6,39,40].…”

Section: Factors Influencing the Melanin Productionmentioning

confidence: 99%

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Sponchiado¹,

Sousa²,

Andrade³

et al. 2017

Melanin

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Production of the microbial pigments is one of the emerging fields of research due to a growing interest of the industry for safer products, easily degradable and eco-friendly. Fungi constitute a valuable source of pigments because they are capable of producing high yields of the substance in the cheap culture medium, making the bioprocess economically viable on the industrial scale. Some fungal species produce a dark-brown pigment, known as melanin, by oxidative polymerization of phenolic compounds, such as glutaminyl-3,4-dihydroxybenzene (GDHB) or catechol or 1,8-dihydroxynaphthalene (DHN) or 3,4-dihydroxyphenylalanine (DOPA). This pigment has been reported to act as "fungal armor" due to its ability to protect fungi from adverse conditions, neutralizing oxidants generated in response to stress. Apart from the scavenging activity, melanin exhibits other biological activities, including thermoregulatory, radio-and photoprotective, antimicrobial, antiviral, cytotoxic, anti-inflammatory, and immunomodulatory. Studies have shown that the media composition and cultivation conditions affect the pigment production in fungi and the manipulation of these parameters can result in an increase in pigment yield for large-scale pigment production. This chapter presents a comprehensive discussion of the research on fungal melanin, including the recently discovered biological activities and the potential use of this pigment for various biotechnological applications in the fields of biomedicine, dermocosmetics, materials science, and nanotechnology.

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Section: Factors Influencing the Melanin Productionmentioning

confidence: 99%

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Sponchiado¹,

Sousa²,

Andrade³

et al. 2017

Melanin

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“…Incidentally, the fungal pigments are natural without creating undesirable effects when they enter the environment. Considering the toxic effects of the synthetic dyes, the natural dyes are eco-friendly and easily degradable since they cause no detrimental effects [11].…”

Section: Introductionmentioning

confidence: 99%

Aspergillus Terreus Kmbf1501 a Potential Pigment Producer Under Submerged Fermentation

Akilandeswari

Pradeep

2017

Int J Pharm Pharm Sci

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Objective: The present study was aimed to identify the fungal isolate from soil and to understand the different optimized parameters better to facilitate the pigment production that has high yield and stability.Methods: Aspergillus sp. was isolated from Western Ghats soil by the conventional serial dilution technique and assessed as a potential pigment producer. Different broth medium such as potato dextrose broth (PDB), czapek-dox broth (CDB), malt extract broth (MEB), rose bengal broth (RBB), sabouraud dextrose broth (SDB), yeast malt extract broth (YEMB), pH (3-9), temperature (24, 27, 30, 33, 37 and 40 °C), carbon (lactose,glucose,sucrose, maltose, galactose and fructose) and nitrogen source (peptone, yeast extract, urea and inorganic nitrogen sources like potassium nitrate, ammonium chloride and sodium nitrate), mineral salts such as sodium dihydrogen phosphate (Na2H2Po4), magnesium sulphate (Mg2So4), calcium chloride (CaCl2), copper sulphate (Cu2So4), potassium dihydrogen phosphate (KH2Po4) and manganese sulphate (Mn2So4) and inoculum age (2-7 d) of the medium related to high pigment production were analysed.Results: Aspergillus terreus KMBF1501 was identified by ribosomal DNA sequencing showing 99% similarity with other Aspergillus terreus and the accession number (KX113516) was assigned. The optimum culture conditions for pigment production by Aspergillus terreus KMBF1501 was achieved at pH 5 (0.563±0.012 nm), temperature of 27 °C (0.382±0.001 nm) with glucose (0.501±0.002 nm) as carbon source, peptone (2.147±0.004 nm) as nitrogen source, Mg2SO4 (0.401±0.001 nm) as mineral salt and 4 d (0.324±0.001 nm) of inoculum age in PDB (0.761±0.006 nm). Conclusion:Aspergillus terreus KMBF1501 produced maximum pigment when cultured in modified PDB than in common PDB medium. The high concentration of the pigment can be used for various industrial purposes.

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“…Extracellular pigment is extracted from media because it is spread outside the cells (Xiong et al 2015;Akilandeswari & Pradeep 2016). Pigment production depends on several conditions, such as nutrient in media, light intensity, pH, trace elements, temperature and agitation (Mugesh et al 2014;Bühler et al 2015;Patil et al 2015;Shi et al 2015).…”

Section: Antibacterial Activity Of Red Pigment Produced From Fungus Rmentioning

confidence: 99%

Antibacterial Activity of Red Pigment Isolated From Coastal Endophytic Fungi Against Multi-Drug Resistant Bacteria

et al. 2017

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Multidrug-resistant (MDR) bacteria infections become a serious problem for these several decades. To solve this issue, finding of new antibiotics candidate in an urgency. Natural pigment is known to has biological activity against pathogenic bacteria. Coastal fungi are unexplored source of natural pigment to fight MDR bacteria. This research was aimed to isolate coastal endophytic fungi from smooth ant plant (Hydophytum formicarum), to screen endophytic fungi which produce red pigment, to extract the red pigment, to determine antibacterial activity of the red pigment and to identify the coastal endophytic fungi producing the red pigment. In this study, 7 fungi were isolated as endophytic fungi from H. formicarum. There were 3 isolates which produced extracellular pigment i.e. RS 1A which produced red pigment, RS 3 produced black pigment and RS 6A produced yellow pigment. Our study focused on red pigment which is produced by endophytic fungus strain RS 1A. The yield of red pigment was 8.8657% (w/w). This study showed that red pigment had antibacterial activity against Escherichia coli, Acinetobacter baumannii and Proteus mirabilis strain MDR. Judging from molecular and morphological identification, the endophytic fungus strain RS 1A was identified as Aspergillus versicolor.

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Exploration of industrially important pigments from soil fungi

Cited by 82 publications

References 81 publications

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Aspergillus Terreus Kmbf1501 a Potential Pigment Producer Under Submerged Fermentation

Antibacterial Activity of Red Pigment Isolated From Coastal Endophytic Fungi Against Multi-Drug Resistant Bacteria

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