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DOI: 10.18830/issn2238-362x.v5.n1.2015.04
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Explorando E Desvendando Regras Da Percepção

Abstract: Para as ciências humanas a arte é uma categoria especial de atividade humana. Por exemplo, discute-se perspectivas diferentes sobre o que faz com que um objeto seja ou não arte? Alguns pontos de vista filosóficos descrevem a arte como "imitação" (Platão), "redenção" (Nietzsche), ou "comunicação de sentimento" (Tolstoi); há mais visões recentes de arte como "fetiche" (Adrian Piper), "virtual" (Douglas Davis) ou computacional, no nosso caso. A arte também é definida do ponto de vista dos espectadores, ou sej… Show more

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“…[11,21] Moreover, biochemical experiments found that Tau isoforms with four (R1-R4) repeats are more competent at promoting microtubules assembly than the isoforms with three (R1, R3, and R4) repeats. [25][26][27][28] Tau is one of the major pathophysiologically relevant proteins in the AD, which hyperphosphorylated Tau aggregates into paired helical filaments (PHFs) and further causes neurodegeneration. [25][26][27][28] Tau is one of the major pathophysiologically relevant proteins in the AD, which hyperphosphorylated Tau aggregates into paired helical filaments (PHFs) and further causes neurodegeneration.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…[11,21] Moreover, biochemical experiments found that Tau isoforms with four (R1-R4) repeats are more competent at promoting microtubules assembly than the isoforms with three (R1, R3, and R4) repeats. [25][26][27][28] Tau is one of the major pathophysiologically relevant proteins in the AD, which hyperphosphorylated Tau aggregates into paired helical filaments (PHFs) and further causes neurodegeneration. [25][26][27][28] Tau is one of the major pathophysiologically relevant proteins in the AD, which hyperphosphorylated Tau aggregates into paired helical filaments (PHFs) and further causes neurodegeneration.…”
Section: Introductionmentioning
confidence: 99%
“…[13,[22][23][24] Most neurodegenerative diseases including Alzheimer's disease (AD) are caused by abnormal intracellular deposition of insoluble proteins. [25][26][27][28] Tau is one of the major pathophysiologically relevant proteins in the AD, which hyperphosphorylated Tau aggregates into paired helical filaments (PHFs) and further causes neurodegeneration. [29,30] The progressive accumulation of neurofibrillary tangles (NFTs) is one of the neuropathological hallmarks of the AD which the core of these PHFs is belonging to the repeat domains and its flanking regions.…”
Section: Introductionmentioning
confidence: 99%