Abstract:A sample, fast, precise and accurate spectrophotometric method to the quantitative determination of metoclopramide hydrochloride (MCP) in pure and pharmaceutical preparations, a simple, sensitive and high-purity method has been developed. This method is based on the diazotization of the primary amine group of metoclopramide hydrochloride by reaction hydrochloric acid with sodium nitrite followed by conjugation in an alkaline medium with 8-hydroxyquinoline against the reagent blank. The effect of several acids … Show more
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