Experimental Study of Flocculation of Bentonite and Alcaligenes Eutrophus in a Batch Oscillatory Baffled Flocculator

Ni, Xiongwei; Cosgrove, J. A.; Cumming, R. H.; Greated, Clive; Murray, K. R.; Norman, Paul R.

doi:10.1205/026387601528507

Cited by 19 publications

(12 citation statements)

References 15 publications

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“…Table 6 lists the anaerobic bioprocesses previously conducted in an OBR. Flocculation is a process by which small particles aggregate, with the aid of a polymer, to form flocs large enough to settle or be filtered: commonly used industrially, for example, in water and wastewater treatment [75]. Traditionally, STRs known as stirred tank flocculators are used for this process to provide agitation essential for generating particle collisions.…”

Section: Bioprocesses Using Cellular Componentsmentioning

confidence: 99%

“…Traditionally, STRs known as stirred tank flocculators are used for this process to provide agitation essential for generating particle collisions. An OBR has been used as a flocculation device for the bacterium Alcaligenes eutrophus and compared with an STR, assessing the percentage flocculation at various operating conditions [75]. Although 100 per cent flocculation was not reached in the OBR, a comparison with another study [90] demonstrated that, for similar starting bacterial concentrations, fuller flocculation was achieved in the OBR at much lower shear rates.…”

Section: Bioprocesses Using Cellular Componentsmentioning

confidence: 99%

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Biological processing in oscillatory baffled reactors: operation, advantages and potential

Harvey

et al. 2013

Interface Focus.

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The development of efficient and commercially viable bioprocesses is essential for reducing the need for fossil-derived products. Increasingly, pharmaceuticals, fuel, health products and precursor compounds for plastics are being synthesized using bioprocessing routes as opposed to more traditional chemical technologies. Production vessels or reactors are required for synthesis of crude product before downstream processing for extraction and purification. Reactors are operated either in discrete batches or, preferably, continuously in order to reduce waste, cost and energy. This review describes the oscillatory baffled reactor (OBR), which, generally, has a niche application in performing ‘long’ processes in plug flow conditions, and so should be suitable for various bioprocesses. We report findings to suggest that OBRs could increase reaction rates for specific bioprocesses owing to low shear, good global mixing and enhanced mass transfer compared with conventional reactors. By maintaining geometrical and dynamic conditions, the technology has been proved to be easily scaled up and operated continuously, allowing laboratory-scale results to be easily transferred to industrial-sized processes. This is the first comprehensive review of bioprocessing using OBRs. The barriers facing industrial adoption of the technology are discussed alongside some suggested strategies to overcome these barriers. OBR technology could prove to be a major aid in the development of commercially viable and sustainable bioprocesses, essential for moving towards a greener future.

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Section: Bioprocesses Using Cellular Componentsmentioning

confidence: 99%

Section: Bioprocesses Using Cellular Componentsmentioning

confidence: 99%

Biological processing in oscillatory baffled reactors: operation, advantages and potential

Harvey

et al. 2013

Interface Focus.

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“…This definition can be usefully interpreted as being a process development involving dramatically smaller equipment which leads to: Improved control of reactor kinetics giving higher selectivity, reduced waste products, higher energy efficiency, reduced capital costs and reduced inventory, improved intrinsic safety and fast response times. Low and uniform shear is one of the important parameters that should be considered in bioprocesses especially when handling shear-sensitive materials, such as certain pharmaceutical crystals and in flocculators (Ni et al, 2001). Intensifying equipment in bioprocesses used to enhance heat transfer and gas-liquid mass transfer which is often the limiting factor in aerobic systems (Reay et al, 2013).…”

Section: Equipmentmentioning

confidence: 99%

Process Intensification for Production and Recovery of Biological Products

Vaghari¹,

Eskandari²,

Sobhani³

et al. 2015

American Journal of Biochemistry and Biotechnology

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Bioprocesses are important biological reactions which need several sophisticated methods and equipment to produce many novel and important compounds which some of them are traditionally produced by synthetic chemical reactions. In bioprocesses, the products are often produced in a dilute environment and finally they require a high purity. Because of that, downstream processes are usually included a large number of separation steps. Size and capital costs of the equipment are two main limitations of using bioprocesses at industrial scale. Bioprocess intensification by minimizing, substitution, moderation and simplification of the methods and equipment, drastically leads to sustainable processes. This study looks at intensification of the emerging equipment and operational methods and their advantages to lead smaller and cleaner bioprocess plants which in turn, increases production efficiency and quality and decreases byproducts formation, capital cost and energy consumption.

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“…fl occulators ( Ni et al, 2001 ). Low and uniform shear is one of the aspects of OBRs that should allow them to be used as bioreactors.…”

Section: Biological Applicationsmentioning

confidence: 99%

Reactors

2008

Process Intensification

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Experimental Study of Flocculation of Bentonite and Alcaligenes Eutrophus in a Batch Oscillatory Baffled Flocculator

Cited by 19 publications

References 15 publications

Biological processing in oscillatory baffled reactors: operation, advantages and potential

Biological processing in oscillatory baffled reactors: operation, advantages and potential

Process Intensification for Production and Recovery of Biological Products

Reactors

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