“…21 In pre-clinical testing, primary implant stability is evaluated by the relative movements between bone and implant during physiological loading. 14,18,19,[22][23][24][25] It is influenced by bone density, surgical technique, implant material and design, the level of press-fit, and the magnitude and direction of the physiological loads. 14,18,19,23,24,[26][27][28][29] Regarding the response of human bone cells, small micromotions at the boneimplant interface are improving cell differentiation and bone formation at the interface.…”