Experimental Labyrinthotomy in Monkeys by Argon and Carbon Dioxide Lasers

Wilpizeski, Chester R.

doi:10.1177/019459988108900211

Cited by 8 publications

(5 citation statements)

References 6 publications

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“…Over the past decade a great deal of work has been done on hearing preservation with selective occlusion or ablation of the semicircular canals. 1–25 Posterior semicircular canal occlusion has gained widespread popularity in the treatment of intractable benign paroxysmal vertigo because of its high rate of success and very low rate of hearing loss. 5–16,18 Selective ablation of the semicircular canals has also been used to improve access to the petrous apex and clivus tumors, also with low rates of hearing loss.…”

Section: Introductionmentioning

confidence: 99%

Hearing Preservation With Labyrinthine Ablation in Otitis Media

2000

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Objectives: Iatrogenic fenestration of the inner ear in the presence of otitis media is commonly associated with permanent hearing loss. Hearing can generally be preserved when the vestibular labyrinth is ablated in a controlled manner in noninflamed ears. The purpose of this study was to examine the feasibility of hearing preservation with violation of the inner ear in the presence of middle ear inflammation. Study Design: Prospective and controlled animal model. Methods: Otitis media was induced bilaterally in pigmented guinea pigs with transtympanic injection of Streptococcus pneumoniae, nontypeable Haemophilus influenzae, or formalin-killed nontypeable H influenzae. Two to 4 days after injection, the horizontal canal of one ear was transected and sealed. Hearing was tested before and after labyrinthine ablation. Results: Otitis media was induced in all ears. Bacterial cultures were positive in 19 of 20 S pneumoniaeinjected ears, and in 10 of 16 nontypeable H influenzae-injected ears. One week after surgery, elevation of click thresholds (> 15 dB) was encountered in none of the fenestrated or unfenestrated S pneumoniaeinfected ears, in two of six unfenestrated and three of six fenestrated nontypeable H influenzae-infected ears, and in one of five killed-nontypeable H influenzae-injected ears both with and without fenestration. Conclusions: These data suggest that ablation of a semicircular canal in the presence of middle ear inflammation or infection does not necessarily lead to profound sensorineural hearing loss. Hearing loss associated with iatrogenic violation of the semicircular canals may be more dependent on factors other than the presence of nonspecific middle ear inflammation.

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Section: Introductionmentioning

confidence: 99%

Hearing Preservation With Labyrinthine Ablation in Otitis Media

2000

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“…Die Methode der laserchirurgischen Okklusion des hinteren Bogengangs schnitt in einer Studie beim Vergleich mit den Ergebnissen der konventionell-chirurgischen Okklusion des hinteren Bogengangs sogar besser ab [134]. Das Verfahren geht auf Studien von Wilpizeski und Anthony zurück [135,136]. Sowohl Argon-und CO 2 -Lasersysteme sind für die Koagulation des Endolymphschlauches geeignet [137,138].…”

Section: 5unclassified

Gestörtes GleichgewichtWiederherstellende Verfahren bei gestörtem Gleichgewicht

Walther

2005

Laryngorhinootologie

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Abb. 3 a Bei einer gesunden Person ist die Richtung der Rotation beider Augen bei Kopfbewegungen entgegengesetzt zur Richtung der Kopfbewegung. Die Rotationsachsen von Kopf und Augen stehen zueinander parallel. Die Geschwindigkeit der Augenrotation entspricht der Geschwindigkeit der Kopfrotation (nach [68]). b Im Falle eines einseitigen Vestibularisausfalls ist die Geschwindigkeit der Augenrotation geringer als die Geschwindigkeit der Kopfbewegung. Die Rotationsachsen von Kopf und Augen unterscheiden sich. Beides führt zu einem unscharfen, verwischten retinalen Abbild (nach [68]).

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“…It has been postulated that laser coagulation might be such an atraumatic, nonmechanical means of sealing the membranous labyrinth with selective vestibular ablation. Wilpizeski et al 25,26 and Anthony and Ackley 19,27 demonstrated that argon laser irradiation to the vestibular labyrinth does not adversely affect hearing. Unfortunately, it also does not consistently occlude the membranous labyrinth.…”

Section: Figmentioning

confidence: 99%

“…This course will be held Feb. [26][27][28]1998, in Erlangen, Germany. It will feature end-aural tympanomeatoplasty and the enlarged middle fossa approach for acoustic neurinomas, live surgery, and temporal bone microdissections.…”

Section: Compact Training Course In Ear Surgerymentioning

confidence: 99%

Triple Semicircular Canal Occlusion in the Guinea Pig

Antonelli

Bouchard

Kartush

et al. 1997

Otolaryngol.--head neck surg.

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Hearing preservation is possible with translabyrinthine procedures, but the optimal means of sealing the remaining labyrinth has not been determined. The purpose of this study was to compare the effects of mechanical and nonmechanical (CO2 laser-assisted) triple semicircular canal occlusion on hearing in the guinea pig. All three semicircular canals of 19 guinea pigs were treated with one of four techniques: fenestration without packing (control), fenestration with packing, CO2 laser coagulation of the membranous canal without packing, or laser coagulation with packing. Six weeks postoperatively, electrocochleographic thresholds were significantly elevated in one of five ears treated with packing alone, in one of five ears treated with laser and packing, in two of five ears treated with the laser alone, and in all four control ears. Thresholds were significantly elevated in control versus occluded ears ( p < 0.05). There were no significant differences between the ears treated with laser or packing. These findings suggest that hearing can be preserved in triple canal occlusion by means of sealing the membranous labyrinth with either CO2 laser coagulation or mechanical packing. Further study on the feasibility of hearing preservation with complete labyrinthectomy is warranted.

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Experimental Labyrinthotomy in Monkeys by Argon and Carbon Dioxide Lasers

Cited by 8 publications

References 6 publications

Hearing Preservation With Labyrinthine Ablation in Otitis Media

Hearing Preservation With Labyrinthine Ablation in Otitis Media

Gestörtes GleichgewichtWiederherstellende Verfahren bei gestörtem Gleichgewicht

Triple Semicircular Canal Occlusion in the Guinea Pig

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