Experimental infection of wild boar with pseudorabies virus isolates of different virulence

Müller, Thomas; Teuffert, Jürgen; Zellmer, R.; Conraths, Franz Josef

doi:10.1051/vetres:2000034

Cited by 2 publications

(3 citation statements)

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“…They are genetically different from isolates obtained from domestic pigs (Müller et al., 2000). Although AD in wild boar is not considered to be a major threat, a virus transmission to domestic pigs cannot be ruled out completely (Müller et al., 2000, 2001a).…”

Section: Introductionmentioning

confidence: 99%

Long‐Term Studies on Maternal Immunity for Aujeszky's Disease and Classical Swine Fever in Wild Boar Piglets

Müller

Teuffert

Staubach

et al. 2005

Journal of Veterinary Medicine, Series B

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The aim of the studies was to fathom the duration and the role of maternal immunity for Aujeszky's disease (AD) and classical swine fever (CSF) in wild boar offspring. In one experiment, two wild boar sows were infected with a low pathogenic pseudorabies virus (PRV) in 1999. A total of 51 offspring was born between 1999 and 2002 and was monitored for PRV maternal antibodies. In a second experiment, the maternal immunity for CSF was analysed. Therefore, a sow was orally vaccinated against CSF using vaccine baits containing the live-attenuated C-strain vaccine. The vaccination took place in January 1999. The sow gave birth to four piglets in 2001 and to two piglets in 2002. With respect to maternal immunity for AD, some piglets reacted positive in the ELISA up to 27-week post-partum while in the neutralization test antibodies were detected up to 15-week post-partum. The calculated half-life of neutralizing antibodies was 21 days. Regarding CSF, the neutralization titres of maternal antibodies dropped continuously reaching values of < or =10 ND50 20-week post-partum. After the 12th week post-partum, most of the sera reacted negative in the ELISA. However, after the third month, low levels of neutralization titres were still detectable. The results are discussed with respect to the epidemiology and control of both diseases in wild boar populations.

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Section: Introductionmentioning

confidence: 99%

Long‐Term Studies on Maternal Immunity for Aujeszky's Disease and Classical Swine Fever in Wild Boar Piglets

Müller

Teuffert

Staubach

et al. 2005

Journal of Veterinary Medicine, Series B

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“…All UL44 sequences were analyzed in previous studies (10,9,20,12), with the exception of sequences from China, South Korea and Malaysia. The 109 sequences were named according to the name of the isolate in …”

Section: Suhv Sequencesmentioning

confidence: 99%

“…SuHV-1 is classified into different genotypes based on restriction endonuclease analysis (3), but more recent studies conducted in Brazil, the United States and Europe have characterized viral strains based on partial sequencing of UL44 focusing on the region encoding the N-terminal portion of glycoprotein C (10,9,20,12). The UL44 gene is one of the most variable regions of the SuHV-1 genome (17).…”

Section: Introductionmentioning

confidence: 99%

Pseudorabies virus can be classified into five genotypes using partial sequences of UL44

Fonseca¹,

Camargos²,

Sales³

et al. 2012

Braz. J. Microbiol.

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Suid herpesvirus 1 (SuHV-1) is the causative agent of pseudorabies (PR), a disease of great importance due to the huge losses it causes in the swine industry. The aim of this study was to determine a method for genotyping SuHV-1 based on partial sequences of the gene coding for glycoprotein C (gC) and to elucidate the possible reasons for the variability of this region. A total of 109 gCsequences collected from GenBank were divided into five major groups after reconstruction of a phylogenetic tree by Bayesian inference. The analysis showed that a portion of gC (approximately 671 bp) is under selective pressure at various points that coincide with regions of protein disorder. It was also possible to divide SuHV-1 into five genotypes that evolved under different selective pressures. These genotypes are not specific to countries or continents, perhaps due to multiple introduction events related to the importation of swine.

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Experimental infection of wild boar with pseudorabies virus isolates of different virulence

Cited by 2 publications

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Long‐Term Studies on Maternal Immunity for Aujeszky's Disease and Classical Swine Fever in Wild Boar Piglets

Long‐Term Studies on Maternal Immunity for Aujeszky's Disease and Classical Swine Fever in Wild Boar Piglets

Pseudorabies virus can be classified into five genotypes using partial sequences of UL44

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