2006
DOI: 10.1146/annurev.fluid.38.050304.092022
|View full text |Cite
|
Sign up to set email alerts
|

Experimental Fluid Mechanics of Pulsatile Artificial Blood Pumps

Abstract: The fluid mechanics of artificial blood pumps has been studied since the early 1970s in an attempt to understand and mitigate hemolysis and thrombus formation by the device. Pulsatile pumps are characterized by inlet jets that set up a rotational "washing" pattern during filling. Strong regurgitant jets through the closed artificial heart valves have Reynolds stresses on the order of 10,000 dynes/cm 2 and are the most likely cause of red blood cell damage and platelet activation. Although the flow in the pump … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
91
0
5

Year Published

2007
2007
2020
2020

Publication Types

Select...
5
2
1

Relationship

1
7

Authors

Journals

citations
Cited by 101 publications
(97 citation statements)
references
References 50 publications
(63 reference statements)
1
91
0
5
Order By: Relevance
“…PIV has been used extensively in previous Penn State fluid mechanic investigations of the 50 cc device [6,9,12,13,15,16]. For this study, an Nd:YAG laser, part of a Gemini PIV 15 system (New Wave Research, Inc., Fremont, CA) directed two 532 nm polarized lasers, capable of delivering 120 mJ laser pulsations with a 5-10 ns pulse width, to an attenuator to regulate energy exiting the laser shutter.…”
Section: Methodsmentioning
confidence: 99%
See 2 more Smart Citations
“…PIV has been used extensively in previous Penn State fluid mechanic investigations of the 50 cc device [6,9,12,13,15,16]. For this study, an Nd:YAG laser, part of a Gemini PIV 15 system (New Wave Research, Inc., Fremont, CA) directed two 532 nm polarized lasers, capable of delivering 120 mJ laser pulsations with a 5-10 ns pulse width, to an attenuator to regulate energy exiting the laser shutter.…”
Section: Methodsmentioning
confidence: 99%
“…It has been estimated that nearly 81 Â 10 6 Americans are affected by some form of cardiovascular disease, with greater than 5 Â 10 6 diagnosed with heart failure (HF) [1]. The American Heart Association/American College of Cardiology has classified the progression of HF into four stages (A-D) of increasing severity which has led to guidelines for diagnosis and treatment.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…As known the ventricles contract after 300 ms from the beginning of the cardiac cycle (Ventricles Contraction Time -t VC ), so a constant coefficient (CC) can be determined as T ECG /t VC to have CC=2.667 [10]. It is clear that the ventricles contraction time changes according to the change in HR.…”
Section: Ecg Systemmentioning
confidence: 99%
“…Em bombas rotativas de sangue, as tensões de cisalhamento elevadas que geralmente ocorrem em torno das bordas dos impulsores podem chegar a valores três ordens de grandeza superiores em relação aos máximos típicos na circulação sanguínea humana (Sallam e Hwang, 1984), (Grigioni et al, 1999), (Lu et al, 2001), (Chua et al, 2007), , . Enquanto o limite superior de tensão de cisalhamento que ocorre no sistema circulatório humano chega próximo ao valor de 15 Pa (Koutsiaris et al, 2013), os valores aos quais as hemácias podem ser submetidas quando atravessam dispositivos de assistências circulatória, tais como bombas centrífugas, podem atingir até 1000 Pa (Deutsch et al, 2006).…”
Section: O Problema Da Hemóliseunclassified