Experimental Data on Chronic Magnesium Deficiency

Aranda, Pilar; Planells, Elena; Sánchez, Cristina; Quintero, B.; Llopis, Juan

doi:10.1007/978-1-84628-483-0_9

Cited by 3 publications

(3 citation statements)

References 51 publications

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“…Being an essential cofactor in reactions involving phosphorylation, magnesium deficiency could impair the insulin signal transduction pathway [25]. Some authors have linked magnesium depletion in T2D to a low magnesium intake in the Western diet [27,28].…”

Section: Discussionmentioning

confidence: 99%

Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey

Simic

Hansen

Åsvold

et al. 2017

Journal of Trace Elements in Medicine and Biology

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Several epidemiological studies have indicated that a number of trace elements may play a role in type 2 diabetes (T2D). We investigated the association between prevalent T2D and the concentrations of 25 trace elements in whole blood, and the relationships between T2D duration and blood levels of the trace elements that we found to be related to T2D prevalence. In this population based case-control study, 267 patients with self-reported T2D and 609 controls (frequency matched), were selected from the third Nord-Trøndelag Health Survey. Trace element blood levels were determined by high resolution inductively coupled plasma-mass spectrometry. Multivariable conditional logistic regression and multivariable linear regression were used to estimate associations. The prevalence of T2D was positively associated with boron, calcium and silver, and inversely associated with indium, lead and magnesium (P<0.05). We found no statistical evidence for associations between blood levels of arsenic, bromine, cadmium, cesium, chromium, copper, gallium, gold, manganese, mercury, molybdenum, nickel, rubidium, selenium, strontium, tantalum, thallium, tin and zinc and T2D prevalence. After corrections for multiple testing, associations remained significant for calcium and lead (Q<0.05), and borderline significant for magnesium, silver and boron. With increasing disease duration, higher calcium levels were observed (P<0.05). This study suggests an association between prevalent T2D and blood levels of boron, calcium, indium, lead, magnesium and silver.

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Section: Discussionmentioning

confidence: 99%

Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey

Simic

Hansen

Åsvold

et al. 2017

Journal of Trace Elements in Medicine and Biology

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“…This scaffold geometry improves the cellular migration, the ingrowth of the new tissue, the transport of body fluid, and the vascularization through the material. [26,27] Regarding biocompatibility, magnesium is a biocompatible metallic material representing the fourth most abundant cation in the body and the second most important, after potassium in the intracellular medium. [4][5][6]9,10] Currently, research with biodegradable metallic materials such as Mg and its alloys, [7,8,[11][12][13][14][15][16][17][18][19][20] Fe and Fe-Mn alloys, [21,22] and W [23][24][25] is being carried out in the field of medicine.…”

Section: Introductionmentioning

confidence: 99%

Processing of Magnesium Porous Structures by Infiltration Casting for Biomedical Applications

et al. 2013

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Magnesium and its alloys are currently considered to be a promising metallic biomaterial. The interest in magnesium alloys arises from their biocompatibility, bioabsorbility, and especially from their mechanical properties, which are more compatible to those of human bone than the mechanical properties of other metallic biomaterials, such as stainless steel and titanium. A medical application in which magnesium is gaining interest is regenerative medicine where scaffolds are used to create tissues from cells. For its application in regenerative medicine, the scaffolds have to present a 3D open-cell structure. The main purpose of the present research is to set up the fabrication procedure necessary to manufacture porous magnesium scaffolds; for this the replication (infiltration) process has been used and adapted to process magnesium alloys, processing five different biodegradable magnesium alloys (AZ91E, WE43, ZM20, ZWM200, and ZXM200).

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“…4,5 In fact, most of the magnesium in the human body is in the skeleton, being an essential component for bone growth and maturation. 25,26 Regarding biocompatibility, magnesium is a biocompatible metallic material representing the fourth most abundant cation in the body and the second most important, after potassium, in the intracellular medium. 27 And finally, regarding its ability to be bioabsorbed, the cations generated due to corrosion are efficiently regulated by the body.…”

Section: Introductionmentioning

confidence: 99%

Effectivity of fluoride treatment on hydrogen and corrosion product generation in temporal implants for different magnesium alloys

Trinidad

Arruebarrena

Marco

et al. 2013

Proc Inst Mech Eng H

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The increasing interest on magnesium alloys relies on their biocompatibility, bioabsorbility and especially on their mechanical properties. Due to these characteristics, magnesium alloys are becoming a promising solution to be used, as temporary implants. However, magnesium alloys must overcome their poor corrosion resistance. This article analyses the corrosion behaviour in phosphate-buffered saline solution of three commercial magnesium alloys (AZ31B, WE43 and ZM21) as well as the influence of fluoride treatment on their corrosion behaviour. It is shown that the corrosion rate of all the alloys is decreased by fluoride treatment. However, fluoride treatment affects each alloy differently.

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Experimental Data on Chronic Magnesium Deficiency

Cited by 3 publications

References 51 publications

Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey

Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey

Processing of Magnesium Porous Structures by Infiltration Casting for Biomedical Applications

Effectivity of fluoride treatment on hydrogen and corrosion product generation in temporal implants for different magnesium alloys

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