Experimental correction of metabolic changes in mouth at long-term hypoacidity by multiprobiotic "Symbiter acidophilic"

Manko, AM; Neporada, KS; Sukhomlyn, A. A.; Ghasemzadeh, J; Beregova, T.; Yankovskiy, D. S.

doi:10.15407/fz60.05.099

Cited by 2 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Stomach disorders of the acid-base balance and various pathogens 4 , 5 can cause many lesions, increasing the probability of triggering cancers 6 – 8 . Hypoacidity of the gastric juice is a dangerous state, which leads to dysbiosis, putrefactive processes, suppression of proteolytic enzyme activation and stomach cancer 9 . On the other hand, hyperacidity of gastric juice between meals is one cause of ulcers 10 .…”

Section: Introductionmentioning

confidence: 99%

Peripheral N-methyl-D-aspartate receptor localization and role in gastric acid secretion regulation: immunofluorescence and pharmacological studies

Golovynska

Берегова

Falalyeyeva

et al. 2018

Sci Rep

View full text Add to dashboard Cite

The enteric nervous system (ENS) and a glutamate receptor (GluR), N-methyl-D-aspartate receptor (NMDAR), participate in gastric acid secretion (GAS) regulation. NMDARs are localized in different stomach cells; however, knowledge of NMDAR expression and function in the ENS is limited. In the present study, we clarified the types of stomach cells that express the NMDARs that are involved in GAS regulation. The pharmacological method of isolated stomach perfusion by Ghosh and Shild combined with direct mapping of NMDARs by fluorescence microscopy in the rat stomach was employed. By immunofluorescence labeling with an anti-NMDA-NR1 antibody, NMDARs were found to be highly expressed in nerve cells of the submucosal and myenteric plexuses in the stomach. The exact localization of the NMDARs relevant to GAS and its mechanism of action were determined by stimulating different receptors of neuronal and stomach cells using specific secretagogues for NMDA and by selectively blocking those receptors. NMDARs relevant to GAS stimulation are mainly localized in cholinergic interneurons; however, all of the nerve cells of the submucosal ganglia are involved in the stimulating process. In addition, the NMDARs in parietal cells are involved in gastric acid inhibition via influencing H2-histamine receptors.

show abstract

Section: Introductionmentioning

confidence: 99%

Peripheral N-methyl-D-aspartate receptor localization and role in gastric acid secretion regulation: immunofluorescence and pharmacological studies

Golovynska

Берегова

Falalyeyeva

et al. 2018

Sci Rep

View full text Add to dashboard Cite

show abstract

Syntaxonomy and ecological differentiation of the pioneer vegetation of Ukraine Classes: Isoëto-Nanojuncetea, Bidentetea

Dubyna

Dziuba

Iemelianova

et al. 2021

Environmental &Amp; Socio-Economic Studies

View full text Add to dashboard Cite

The studies of the pioneer vegetation of freshwater shorelines of water bodies are of particular interest owing to the specific ecology of these habitats and the short cycle for their development in which periods of flooding and subsequent drainage alternate. Using the methods of phytosociological classification and cluster analysis based on the interpretation of 414 phytosociological relevés, the syntaxonomic structure of the pioneer vegetation of freshwater shorelines of the water bodies of Ukraine has been established that are represented by the phytosociological classes Isoëto-Nanojuncetea and Bidentetea. The class Isoëto-Nanojuncetea includes 8 associations that belong to 2 alliances and 1 order and the class Bidentetea includes 10 associations belonging to 2 alliances and 1 order. Phytocoenoses of both classes are more typical for the Polissia region and the forest-steppe zone of Ukraine, where there are favourable habitats with a flat relief, low degree of dissection and a high level of soil humidity. Using a DCA ordination analysis of associations their position in ecological space was determined. It was established that the main factors of ecological differentiation for Isoëto-Nanojuncetea habitats are soil humidity, soil aeration, nitrogen content, as well as temperature regime. Differentiation in the hyperspace of abiotic factors of the class Bidentetea occurs mainly along the gradients of soil humidity, salt regime and acidity. The ecological distribution of syntaxa of this class is also significantly influenced by the concentration of mineral nitrogen compounds in the soil.

show abstract

Experimental correction of metabolic changes in mouth at long-term hypoacidity by multiprobiotic "Symbiter acidophilic"

Cited by 2 publications

References 5 publications

Peripheral N-methyl-D-aspartate receptor localization and role in gastric acid secretion regulation: immunofluorescence and pharmacological studies

Peripheral N-methyl-D-aspartate receptor localization and role in gastric acid secretion regulation: immunofluorescence and pharmacological studies

Syntaxonomy and ecological differentiation of the pioneer vegetation of Ukraine Classes: Isoëto-Nanojuncetea, Bidentetea

Contact Info

Product

Resources

About