Experimental Assessment ofMoringa oleiferaLeaf and Fruit for Its Antistress, Antioxidant, and Scavenging Potential UsingIn VitroandIn VivoAssays

Luqman, Suaib; Srivastava, Sangeeta; Kumar, Ritesh; Maurya, Anil Kumar; Chanda, Debabrata

doi:10.1155/2012/519084

Cited by 215 publications

(179 citation statements)

References 50 publications

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“…The generation of free radicals inside the body causes damage to the DNA, and those free radicals are neutralized by the antioxidants present in the medicinal plants which prevent the cancer [24].…”

Section: Introductionmentioning

confidence: 99%

Qualitative and Quantitative Analysis of Secondary Metabolites of Moringa Oleifera and its Anticancer Activity

Devi¹,

Revathi²,

Gopinath³

et al. 2017

ijaidr

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Moringa oleifera is a native on Indian sub-continent and also known for its medicinal property for a long time in Indian history. However in the recent past more and more scientists were interested in identifying the anti-oxidant compound from the plant. The study aimed at identifying effective solvent for anti-cancer activity from M. oleifera. In the present study leaf, pod and bark samples were collected and air dried and their crude extract were isolated using ethanol, methanol petroleum ether, ethyl acetate and water to study their isolation capacity using different methods for alkaloids saponins, protein, flavonoids, carbohydrates, tannins, terpinoids, phenols, glycosides and phytosteroids showed presence in all the components of leaf, pod and bark in one or the other tests however, the extraction was better in petroleum ether, acetone, ethanol and methanol. GCMS analysis of compounds present in the crude extract using acetone, methanol and ethanol revealed six major compounds which were commonly isolated and most of them had anti-oxidant capacity.MTT assay of crude extract showed effective cell inhibition capacity for Hela cell and MCF7 cell lines. Methanol solvent was found to be effective for Hella cell lines and Ethanol was found to be effective for MCF cell lines.

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Section: Introductionmentioning

confidence: 99%

Qualitative and Quantitative Analysis of Secondary Metabolites of Moringa Oleifera and its Anticancer Activity

Devi¹,

Revathi²,

Gopinath³

et al. 2017

ijaidr

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“…They said that antiulcer and antioxidant properties of the leaves of Moringa Oleifera against gastric ulcer in rats, and result revealed the defense mechanism to lipid peroxides and scavenging endogenous reactive oxygen species production. Luqman et al (2012) discovered variation Antioxidant activities between in vitro and in vivo ethanolic extract of Moringa fruit and leaves in comparison with that of aqueous extract, where aqueous extract showed higher potential in vivo while the ethanolic extract of both fruit and leaf of Moringa was greater in the in vitro condition.…”

Section: Antioxidant Effect Of Moringa Oleiferamentioning

confidence: 99%

Antimalarial, antioxidant, antimicrobial properties of Moringa Oliefera Lam: A review

Abdulkadir¹,

Hasan²,

Jahan³

2018

Aust J Crop Sci

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Moringa oliefera Lam (Moringa) has antimalarial, antioxidant, antimicrobial as well as nutritional properties. Different parts of Moringa was used as a folk medicine to cure certain diseases ranging from venomous bites, rheumatism, ascites, circulatory stimulant among. Previous studies showed that different parts of Moringa oleifera have shown various pharmacological properties. However, there is a gap where substantial information is to be updated in the area of antimalarial, antioxidant, antimicrobial effect of the plants. Nevertheless, some part of the plant such as leaves and fruits have been used as vegetables, which serve as an excellent source of vitamins, beta-carotene, calcium, iron, riboflavin and phenolic acid. Therefore, there is an affirmative action that the plant has a vast antimalarial, antioxidant, antimicrobial activity to cure different diseases.

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“…It protects DNA from the damaging effects of pollutants and heavy metals. The extract also increases collagen synthesis, improves cellular viability, and offers skin conditioning and nourishing benefits, resulting in enhanced skin complexion and healthy glow [57,58].…”

Section: Use Of Multifunctional Actives or Combination Of Different Amentioning

confidence: 99%

Guidelines for Formulating Anti-Pollution Products

Mistry¹

2017

Cosmetics

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Anti-pollution skin care and cosmetic products are witnessing a significant growth in the last couple of years due to worsening air quality across the world, and increasing awareness and concern regarding the adverse impact of various environmental pollutants on skin. The various pollutants, like particulate matter, oxides of nitrogen and sulphur, ozone, and polyaromatic hydrocarbons damage skin by different mechanism resulting in skin dryness, loss of firmness, dark spots, uneven skin tone, fine lines and wrinkles, aggravation of acne, and inflammation. The task of developing globally harmonized products is very challenging due differences in skin types according to ethnicity, variation in seasonal weather pattern, differences in benefit expectations, and variances in personal care and cosmetics usage habits of consumers in different regions of the world. However, an increasing understanding about the mechanism by which various pollutants damage the skin manifesting into various extrinsic signs of skin damage and development of various actives that counter the impact of different environmental aggressors has helped formulators to develop different products and to establish efficacy by in vitro and in vivo tests. The article summarizes approaches for formulation development, and a list of few actives classified based in their mechanism action is given. A representative list of products based on their mechanism of action is also given and few potential opportunities for the future are suggested.

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Experimental Assessment ofMoringa oleiferaLeaf and Fruit for Its Antistress, Antioxidant, and Scavenging Potential UsingIn VitroandIn VivoAssays

Cited by 215 publications

References 50 publications

Qualitative and Quantitative Analysis of Secondary Metabolites of Moringa Oleifera and its Anticancer Activity

Qualitative and Quantitative Analysis of Secondary Metabolites of Moringa Oleifera and its Anticancer Activity

Antimalarial, antioxidant, antimicrobial properties of Moringa Oliefera Lam: A review

Guidelines for Formulating Anti-Pollution Products

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