Experiences in Large‐scale Breeding of Simians for Medical Experimentation*

Valerio, Domenico; Pallotta, A. J.; Courtney, K. Diane

doi:10.1111/j.1749-6632.1969.tb56375.x

Cited by 48 publications

(34 citation statements)

References 7 publications

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“…However, it is impossible to ascertain which of the factors is the most important. The exposure time and intensity of the lighting might be important because these conditions differed most from those previously reported for housing rhesus monkeys (Johansson et al, 1968;Valerio et al, 1968;MacDonald, 1971;Wilson et al, 1972), but more work is required to confirm this.…”

Section: Introductioncontrasting

confidence: 42%

“…The breeding season in Northern India has been reported to be November to January (Southwick, Beg & Siddiqi, 1961) and 21% of the control and 6% of the experimental animals were bled in this period. During September to October, considered part of the breeding season of captive animals (Van Wagenen, 1945;Valerio et al, 1968), the proportions were 32 and 56% respectively. In February to March, 46% of the control and 39% of the experimental monkeys were sampled throughout one menstrual cycle.…”

Section: Introductionmentioning

confidence: 99%

“…In February to March, 46% of the control and 39% of the experimental monkeys were sampled throughout one menstrual cycle. The fertility of rhesus monkeys in these months has been reported to be very low (Valerio et al, 1968). Of the observed anovulatory animals, 2 controls were sampled in October and 2 in February, and 1 experimental was sampled in October and 2 in March.…”

Section: Introductionmentioning

confidence: 99%

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Effects of climate-controlled housing on reproductive potential of rhesus monkeys

Barsotti¹,

Abrahamson²,

Marlar³

et al. 1980

Reproduction

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Section: Introductioncontrasting

confidence: 42%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effects of climate-controlled housing on reproductive potential of rhesus monkeys

Barsotti¹,

Abrahamson²,

Marlar³

et al. 1980

Reproduction

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“…With the latter two species, such a seasonal trend of breeding has been reported to disappear gradually year by year after the introduction into laboratory en-vironment (Valerio, Pallotta and Courtney, 1969 not yet large enough to discuss any causes of the different pregnancy lengths between the F1 and P females. Further studies are needed to draw a definite conclusion related to the problem of this kind.…”

Section: Discussionmentioning

confidence: 98%

Breeding of Cynomolgus Monkeys Through Successive Generations by Indoor Cage System

Honjo

Cho

Fujiwara

et al. 1978

JJMSB

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SUMMARY:Vital statistics on the breeding through successive generations were presented for the cynomolgus monkey colony of NIH, Tokyo. The results of this retrospective survey clearly demonstrated the third (F2) and the fourth (Fs) generations could be bred and reared successfully by the indoor caged-breeding system in which either individual timed-mating or group mating procedure was adopted. Several important and difficult problems involved in the production of successive generations of the cynomolgus monkey by our breeding system were discussed from the standpoint of laboratory animal science.

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“…A mating season has been observed in macaques (non-human primates) living in their natural habitat or in an outdoor enclosure : Macaca mulatto (Conoway and Koford, 1964 ;Lancaster and Lee, 1965 ;Neuville, 1968 ;Vandenbergh and Vessey, 1968), Macaca fuscafa (Tokuda, 1962 ;Hanby, Robertson and Phoenix, 1971 ;Eaton, 1972), Macaca sylvana (McRoberts and McRoberts, 1966), Macaca fascicularis (Gauquelin,1968 (Valerio, Pallota and Courtney, 1969 ;Nomura and Ohsawa, 1975 ;Aso et al, 1977) characterized by a period of amenorrhea in the female (Riesen, Meyer and Wolf, 1971) and a decline in male sexual activity (Michael and Keverne, 1971) concomitant with a decreasing blood testosterone level (Plant et al, 1974 ;Robinson et al, 1975 ;Gordon, Rose and Bernstein, 1976 ;Michael and Bonsall, 1977 (fig. 3).…”

Section: Introductionmentioning

confidence: 99%

Annual plasma testosterone cycle and ejaculatory ability in the laboratory-housed crab-eating macaque (Macaca fascicularis)

Dang¹,

Meusy-Dessolle²

1981

Reprod. Nutr. Dévelop.

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Summary. Six fertile and healthy adult Macaca fascicularis males were studied. Radioimmunological assay of the plasma testosterone, sampled without anesthesia in the afternoon at the beginning of each month, showed an annual hormone cycle with a maximum (16.7 ! 1.1 ng/ml) in the fall and a minimum (9.5 ! 0.9 ng/ml) in the spring ( fig. 1). Using the ratio : number of ejaculations/number of trials, the ejaculatory ability of these animals ( fig. 2) was estimated for 10 min in the presence of females between days 12 and 15 of their menstrual cycle. This ability showed no cyclic variation during the year.Comparing the annual variation of testosterone levels in macaque males (Macaca mulatto, Macaca arctoides, Macaca nemestrina, Macaca fascicularis) and man, we found that, except for Macaca arctoides and Macaca nemestrina, the maximal simian levels always coincided with autumn and the minimal levels with spring in spite of the different rearing environments. (table 2).After studying ejaculatory ability and plasma testosterone level in the intact macaque throughout the year and comparing it to the results obtained by Resko and Phoenix (1972), Phoenix et al. (1973) and bVilson (1974, 1975) studying castrated males, we believe that above a minimal level, variation in the plasma testosterone level does not affect male sexual behavior, at least as far as ejaculatory ability is concerned. Moreover, du ring this study we noted that above a maximal plasma testosterone level, varying with the season, the ejaculation rate may be depressed ( fig. 3).Introduction.

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Experiences in Large‐scale Breeding of Simians for Medical Experimentation*

Cited by 48 publications

References 7 publications

Effects of climate-controlled housing on reproductive potential of rhesus monkeys

Effects of climate-controlled housing on reproductive potential of rhesus monkeys

Breeding of Cynomolgus Monkeys Through Successive Generations by Indoor Cage System

Annual plasma testosterone cycle and ejaculatory ability in the laboratory-housed crab-eating macaque (Macaca fascicularis)

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