Experience with the use of tissue adhesives in pediatric endoscopic surgery

Esposito, Ciro; Damiano, Rocco; Settimi, Alessandro; Marco, Marianna De; Maglio, P.; Centonze, Antonella

doi:10.1007/s00464-003-9032-x

Cited by 37 publications

(21 citation statements)

References 13 publications

(15 reference statements)

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“…[22,50] Besides, their use for the obliteration of processus vaginalis during hydrocelectomy has been also reported. [9][10][11][12] Their use with mesh In an experimental trial, Kukleta et al [13] performed mesh fixation in rabbits with CA glue -nBCA (Histoacryl ® ), and did not observe a reaction in muscle tissue during the acute phase. They reported fibroblastic tissue reaction characterized by mildly or moderately inflammatory cells.…”

Section: Priapismmentioning

confidence: 99%

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Cyanoacrylic tissue glues: Biochemical properties and their usage in urology

Ayyıldız

2017

Turkish Journal of Urology

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Tissue adhesives are being used in medical and cosmetic industries and first aid for a long time. But their everyday usage has not been widespread. Only case report information is available about their usage. Despite good and meaningful results after they were used, there is lack of standard information that gives idea of about in which cases they could be helpful. Nowadays, cyanoacrylates are used in the surgery more frequently. In this review, we wanted to oversee the biochemical properties and the urological utilisation areas of cyanoacrylates.

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Section: Priapismmentioning

confidence: 99%

“…[9][10][11][12] If basic principles are obeyed safe use of nBCA for external, and internal applications has been demonstrated both in preclinical, and clinical studies. [13] Cyanoacrylic glues ensure high degree, and strong bonding to biologic tissues when compared with other adhesives.…”

Section: Introductionmentioning

confidence: 99%

Cyanoacrylic tissue glues: Biochemical properties and their usage in urology

Ayyıldız

2017

Turkish Journal of Urology

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“…No biosynthetic materials are currently marketed for use in the gastrointestinal tract. Of the bioprostheses currently on the market most have been studied for soft-tissue repair particularly for abdominal wall reconstruction in cases of gross contamination and inguinal region reconstruction during hernia repair [15][16][17][18]. One that has been investigated for the use in the reconstruction of gastrointestinal, biliary and soft tissue defects is the small-intestine submucosa extracellular matrix (SIS-ECM).…”

Section: Discussionmentioning

confidence: 99%

Gastrotomy closure using bioabsorbable plugs in a canine model

et al. 2007

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The repair of gastric perforation commonly involves simple suture closure using an open or laparoscopic approach. An endolumenal approach using prosthetic materials may be beneficial. The role of bioprosthetics in this instance has not been thoroughly investigated, thus the authors evaluated the feasibility of gastric perforation repair using a bioabsorbable device and quantified gross and histological changes at the injury site. Twelve canines were anesthetized and underwent open gastrotomy. A 1-cm-diameter perforation was created in the anterior wall of the stomach and plugged with a bioabsorbable device. Intralumenal pH was recorded. Canines were sacrificed at one, four, six, eight, and 12 weeks. The stomach was explanted followed by gross and histological examination. The injury site was examined. The relative ability of the device to seal the perforation was recorded, as were postoperative changes. Tissue samples were analyzed for gross and microscopic tissue growth and compared to normal gastric tissue in the same animal as an internal control. A scoring system of -2 to +2 was used to measure injury site healing (-2= leak, -1= no leak and minimal ingrowth, 0= physiologic healing, +1= mild hypertrophic tissue, +2= severe hypertrophic tissue). In all canines, the bioprosthesis successfully sealed the perforation without leak under ex vivo insufflation. At one week, the device maintained its integrity but there was no tissue ingrowth. Histological healing score was -1. At 4-12 weeks, gross examination revealed a healed injury site in all animals. The lumenal portion of the plug was completely absorbed. The gross and histological healing score ranged from -1 to +1. The application of a bioabsorbable device results in durable closure of gastric perforation with physiologic healing of the injury site. This method of gastrotomy closure may aid in the evolution of advanced endoscopic approaches to perforation closure of hollow viscera.

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“…Laparoscopic chemical application (6% iodine) [86] or use of tissue glue [86][87][88][89], talc, and fibrin, in addition to simple suture of the internal ring, has been tried to achieve the desired rates of PPV obliteration [38]. Table 4 shows the time required for laparoscopic surgery of CIH in different studies or using different techniques.…”

Section: Experimental Techniquesmentioning

confidence: 98%

Minimal access surgery of pediatric inguinal hernias: a review

2008

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Inguinal hernia is a common problem among children, and herniotomy has been its standard of care. Laparoscopy, which gained a toehold initially in the management of pediatric inguinal hernia (PIH), has managed to steer world opinion against routine contralateral groin exploration by precise detection of contralateral patencies. Besides detection, its ability to repair simultaneously all forms of inguinal hernias (indirect, direct, combined, recurrent, and incarcerated) together with contralateral patencies has cemented its role as a viable alternative to conventional repair. Numerous minimally invasive techniques for addressing PIH have mushroomed in the past two decades. These techniques vary considerably in their approaches to the internal ring (intraperitoneal, extraperitoneal), use of ports (three, two, one), endoscopic instruments (two, one, or none), sutures (absorbable, nonabsorbable), and techniques of knotting (intracorporeal, extracorporeal). In addition to the surgeons' experience and the merits/limitations of individual techniques, it is the nature of the defect that should govern the choice of technique. The emerging techniques show a trend toward increasing use of extracorporeal knotting and diminishing use of working ports and endoscopic instruments. These favor wider adoption of minimal access surgery in addressing PIH by surgeons, irrespective of their laparoscopic skills and experience. Growing experience, wider adoption, decreasing complications, and increasing advantages favor emergence of minimal access surgery as the gold standard for the treatment of PIH in the future. This article comprehensively reviews the laparoscopic techniques of addressing PIH.

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Experience with the use of tissue adhesives in pediatric endoscopic surgery

Abstract: Tissue adhesives are a very versatile product for use in pediatric laparoscopic surgery. It is likely that their usage will increase as the technology improves and more effective products are developed.

Cited by 37 publications

References 13 publications

Cyanoacrylic tissue glues: Biochemical properties and their usage in urology

Cyanoacrylic tissue glues: Biochemical properties and their usage in urology

Gastrotomy closure using bioabsorbable plugs in a canine model

Minimal access surgery of pediatric inguinal hernias: a review

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