Experience with non-ablative fractional photothermolysis with a dual-mode laser device (1,440/1,320 nm): no considerable clinical effect on hypertrophic/acne scars and facial wrinkles

Abstract

In the literature, non-ablative fractionated photothermolysis (nFP) is accredited with improvement of wrinkles and scars combined with a reduced downtime. The purpose of this work was to evaluate the impact of a combination laser (1,320/1,440 nm) for nFP on hypertrophic scars, acne scars, and facial wrinkles. Thirty-six patients suffering from hypertrophic scars (n = 7), acne scars (n = 9), and wrinkles (n = 20) were treated using a combination Nd:YAG laser [λ(em) = 1,320 and 1,440 nm, pulse duration: 3-ms single pulse, fluence: 8.0-9.0 J/cm(2) (1,320 nm); 2.0-2.5 J/cm(2) (1,440 nm)]. The appearance of the treated condition was evaluated in a retrospective study by two blinded investigators based on follow-up photographs and by patient self-assessment. The frequency of side-effects was also assessed. Both patients and blinded observers rated the treatment results for hypertrophic scars and acne scars as slight improvement, and for wrinkles as equal as compared to baseline. No serious side-effects were reported. The light device used did not lead to a considerable clinical improvement of hypertrophic scars, acne scars, or wrinkles in this study.

Comparison of Epidermal/Dermal Damage Between the Long-Pulsed 1064 nm Nd:YAG and 755 nm Alexandrite Lasers Under Relatively High Fluence Conditions: Quantitative and Histological Assessments

“…5 Among these techniques, the Nd:YAG and Alexandrite lasers present representative treatment characteristics for skin rejuvenation. These lasers can lead to clinical improvements in rhytides and skin texture, 6,7 as well as atrophic acne scars. 8 Moreover, the cosmetic laser dermatology for photoepilation, elimination of varices and pigmented lesions, can also be well managed.…”

Nonablative Fractional Laser Resurfacing for the Treatment of Hypertrophic Scars: A Randomized Controlled Trial

“…Despite the lack of clear efficacy data, nonablative fractional laser therapy (NAFL) has been suggested as a possible treatment option for nonhypertrophic surgical scars [17][18][19][20][21] and hypertrophic burn scars 15 and in the prevention of scars. 22 Two noncontrolled studies 23,24 and one recent RCT 25 suggested a positive effect on HTS.…”

Neue Entwicklungen in der Lasertherapie

“…Als Postulat der nichtablativen FLT gilt eine im Vergleich zur ablativen FLT reduzierte Invasivität bei nahezu unverändert hoher Effektivität. Zu diesem Thema wurde in unserer Klinik im letzten Jahr eine Studie durchgeführt, im Rahmen derer die Effektivität der nichtablativen FLT auf Gesichtsfalten, hypertrophe Narben und Aknenarben evaluiert wurde [44]. Hierzu wurden 36 Patienten mit einem kombinierten Nd:YAG-Laser behandelt [Affirm, Cynosure, Westford, MA, USA; λ em = 1320 und 1440 nm, Pulsdauer: 3 ms, Energiedichte: 8,0-9,0 J/cm 2 (1320 nm), 2,0-2,5 J/ cm 2 (1440 nm)].…”