Abstract:While exogenous metal/metalloid (metal) exposure has
been associated
with reduced human semen quality, no study has assessed the associations
of exogenous metals in human spermatozoa with semen quality. Here,
we developed a strategy to explore the associations between exogenous
metals in spermatozoa at single-cell resolution and human semen quality
among 84 men screened as sperm donors, who provided 266 semen samples
within 90 days. A cellular atlas of exogenous metals at the single-cell
level was created with… Show more
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