Existence of Angiostrongylus cantonensis in rats (Rattus norvegicus) in Grenada, West Indies

Chikweto, Alfred; Bhaiyat, Muhammad Iqbal; Macpherson, C. N. L.; DeAllie, Claude; Pinckney, Rhonda D.; Richards, Christine; Sharma, Ravindra

doi:10.1016/j.vetpar.2009.02.020

Cited by 30 publications

(24 citation statements)

References 14 publications

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“…The available literature only documents one article addressing the environmental presence of A. cantonensis in rats in Grenada Island (Lesser Antilles) in 2009. 21 It may also be noted that our patient suffered from diarrhea, a symptom later explained by a rotavirus coinfection. The noninfectious etiologies of eosinophilic meningitis were unlikely including drug reaction (as the infant had not taken any other medicines before symptom onset) and hematological and inflammatory diseases (due to the young age of the patient).…”

Section: Discussionmentioning

confidence: 56%

“…6 The geographical distribution of 15 In the Caribbean, the parasite has been found in wild rats in the Greater Antilles in Cuba, 16 Dominican Republic, 17 Haiti, 18 Puerto Rico, 19 Jamaica, 20 and in the Lesser Antilles in Grenada only. 21 Figure 1 depicts reported infections in humans and animal hosts in the Caribbean and surrounding areas to date. Several cases have been reported among humans in the Greater Antilles including Cuba, 16,22 Dominican Republic, 23 and Jamaica, 20,24 whereas no human cases have been documented in the Lesser Antilles.…”

Section: Introductionmentioning

confidence: 99%

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First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles

Dard¹,

Piloquet

Qvarnström

et al. 2017

The American Society of Tropical Medicine and Hygiene

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Section: Discussionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles

Dard¹,

Piloquet

Qvarnström

et al. 2017

The American Society of Tropical Medicine and Hygiene

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“…Definitive and intermediate hosts for the parasite include rats and mollusks, respectively [21], [22]. Humans and other mammals are incidental hosts that become infected upon consumption of the third-stage larvae.…”

Section: Introductionmentioning

confidence: 99%

Global Decline in Suitable Habitat for Angiostrongylus ( = Parastrongylus) cantonensis: The Role of Climate Change

2014

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Climate change is implicated in the alteration of the ranges of species worldwide. Such shifts in species distributions may introduce parasites/pathogens, hosts, and vectors associated with disease to new areas. The parasite Angiostrongylus ( = Parastrongylus) cantonensis is an invasive species that causes eosinophilic meningitis in humans and neurological abnormalities in domestic/wild animals. Although native to southeastern Asia, A. cantonensis has now been reported from more than 30 countries worldwide. Given the health risks, it is important to describe areas with potentially favorable climate for the establishment of A. cantonensis, as well as areas where this pathogen might become established in the future. We used the program Maxent to develop an ecological niche model for A. cantonensis based on 86 localities obtained from published literature. We then modeled areas of potential A. cantonensis distribution as well as areas projected to have suitable climatic conditions under four Representative Concentration Pathways (RCP) scenarios by the 2050s and the 2070s. The best model contained three bioclimatic variables: mean diurnal temperature range, minimum temperature of coldest month and precipitation of warmest quarter. Potentially suitable habitat for A. cantonensis was located worldwide in tropical and subtropical regions. Under all climate change RCP scenarios, the center of the projected distribution shifted away from the equator at a rate of 68–152 km per decade. However, the extent of areas with highly suitable habitat (>50%) declined by 10.66–15.66% by the 2050s and 13.11–16.11% by the 2070s. These results conflict with previous studies, which have generally found that the prevalence of tropical pathogens will increase during the 21st century. Moreover, it is likely that A. cantonensis will continue to expand its current range in the near future due to introductions and host expansion, whereas climate change will reduce the total geographic area of most suitable climatic conditions during the coming decades.

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“…3 Meningitis by A. cantonensis was first described in Southeastern Asia and reported in Asia, Africa, and the Caribbean. [3][4][5][6][7][8][9][10][11] In 1981, Cuba was the first country to report this disease in the Americas, 12 and recently, it was reported in Ecuador. 11,13 Previously, the parasite had been found in naturally infected snails of various genera and species in Northeastern Brazil, 14 which also has reported cases of eosinophilic meningitis in the same areas.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Major Immunoglobulins Intrathecal Synthesis Patterns in Ecuadorian and Cuban Patients with Angiostrongyliasis

Padilla-Docal¹,

Dorta‐Contreras²,

Moreira³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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Abstract. Angiostrongylus cantonensis meningitis was first reported in Cuba in 1981, and it was recently reported in South America. The aim of this paper is to evaluate the intrathecal immunoglobulin synthesis patterns from Cuba's and Ecuador's patients with angiostrongyliasis; 8 Ecuadorian patients from two different outbreaks and 28 Cuban patients were studied. Simultaneous blood and cerebrospinal fluid simples were taken. Immunoglobulin (Ig) A, IgM, IgG, and albumin were quantified by radial immunodiffusion. Corresponding Reibergrams were applied. A three-Ig pattern was the most frequent in the two groups, but IgM was presented in all Ecuadorian young mature patients; however, in the Cuban children, only 12 of 28 patients had intrathecal IgM, but about 90% had an IgA and IgG synthesis at time of later puncture. This indicates that, with a larger amount of parasites ingested, clinical symptoms are more severe, and a higher frequency of intrathecal IgM synthesis could be observed. This is discussed as a similarity with the intrathecal IgM synthesis in African trypanosomiasis.

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Existence of Angiostrongylus cantonensis in rats (Rattus norvegicus) in Grenada, West Indies

Cited by 30 publications

References 14 publications

First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles

First Evidence of Angiostrongyliasis Caused by Angiostrongylus cantonensis in Guadeloupe, Lesser Antilles

Global Decline in Suitable Habitat for Angiostrongylus ( = Parastrongylus) cantonensis: The Role of Climate Change

Comparison of Major Immunoglobulins Intrathecal Synthesis Patterns in Ecuadorian and Cuban Patients with Angiostrongyliasis

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