“…We aimed to perform a systematic integrative review on the effects of several adaptogens on depression-related outcomes besides evaluating the potential combination with physical exercise to optimize results. Similar to previous reports in peri- and postmenopausal women [ 89 ] and healthy individuals [ 90 ], it has been found that certain adaptogens might have low-to-moderate clinical effects to relieve anxiety and mild depression [ 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 ]. It is important to note that the number of articles reporting the level of physical activity is very low and null for those combining an exercise program with adaptogen consumption.…”