Exercise intensity: Platelet function and platelet–leukocyte conjugate formation in untrained subjects

Physical Activity in the Prevention and Treatment of Coronary Artery Disease

“…After transmigration of the endothelial layer, these cells differentiate into foam cells and perpetuate the inflammatory process within atherosclerotic plaques 105. A short‐term bout of intense physical activity in untrained healthy subjects is known to increase platelet activity and reactivity and number of platelet‐leukocyte aggregates 106. In patients with CAD, even low levels of physical exercise have been shown to transiently increase platelet aggregability, which might result in coronary occlusion in case of plaque rupture 107.…”

Effect of Crocin and Voluntary Exercise on P53 Protein in Pancreas of Type2 Diabetic Rats

“…20 Nevertheless, exhaustive exercise may be problematic, as they are stressful through production of reactive oxygen species and can cause damage to muscle tissue and other organs, 21 voluntary exercise may be a better model with more beneficial effects. 22 In the animal model of voluntary exercise, the animal has free access to a running wheel and uses the wheel according to its physiological threshold for physical activity. Therefore, the influence of crocin combination with voluntary exercise on pancreases apoptosis following type 2 diabetic rats remains unknown.…”

Release of pro-coagulant microparticles after moderate endurance exercise

“…As PMP and platelet count had different time-course, the increase in PMP is probably caused by exercise-induced platelet activation rather then a simple consequence of the increase in platelet count. Exercise-induced platelet activation was recently reported [12,13].…”