Exercise for fatigue in breast cancer patients: An umbrella review of systematic reviews

Jiang, Mengyao; Ma, Yanhui; Yun, Bei; Wang, Qing; Huang, Can; Han, Lin

doi:10.1016/j.ijnss.2020.03.001

Cited by 28 publications

(30 citation statements)

References 49 publications

(71 reference statements)

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“…While various drugs have been investigated, the evidence supports combined therapeutic exercise (TE) and psychological interventions as the best therapeutic option for CRF management [ 5 ], showing both efficacy and safety for reducing fatigue in BC survivors [ 10 ]. Recent systematic reviews [ 10 , 11 , 12 , 13 ] support the benefits of aerobic and resistance exercise in patients with CRF in agreement with the Guidelines for Exercise Testing and Prescription in the cancer population by the American College of Sports Medicine (ACSM) [ 14 , 15 ]. In addition, TE is recommended in several clinical practice guidelines to reduce other adverse effects derived from cancer treatments, such as pain, depression, or bone and body weigh alterations [ 10 ].…”

Section: Introductionmentioning

confidence: 98%

Effectiveness of Therapeutic Exercise and Patient Education on Cancer-Related Fatigue in Breast Cancer Survivors: A Randomised, Single-Blind, Controlled Trial with a 6-Month Follow-Up

Prieto-Gómez

Yuste-Sánchez

Bailón-Cerezo

et al. 2022

JCM

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This study aimed to determine the effectiveness of therapeutic exercise plus patient therapeutic education on perceived fatigue, functional capacity and pain in breast cancer survivors with cancer-related fatigue. A randomised, single-blind, clinical trial was conducted with a total of 80 breast cancer survivors who presented cancer-related fatigue. Women were randomised into a supervised therapeutic exercise group (STE-G) (n = 40) or an unsupervised exercise group (UE-G) (n = 40). Both interventions included patient therapeutic education and were delivered in three sessions per week over eight weeks. The main outcome was perceived fatigue as assessed by the Spanish version of the Functional Assessment of Chronic Illness Therapy-Fatigue subscale (FACIT-F). Other evaluated outcomes were pain measured on a visual analogue scale, and distance measured using the 6-Minute Walk Test. Data were collected at baseline, immediately post-intervention, and at three and six months after baseline. Significantly greater improvements across all variables were observed in the STE-G throughout the entire follow-up period with the exception of pain. Conclusions: A supervised therapeutic exercise program plus patient therapeutic education significantly reduce perceived fatigue and increase functional capacity in breast cancer survivors suffering from cancer-related fatigue compared to an unsupervised physical exercise program based on individual preferences with patient therapeutic education.

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Section: Introductionmentioning

confidence: 98%

Effectiveness of Therapeutic Exercise and Patient Education on Cancer-Related Fatigue in Breast Cancer Survivors: A Randomised, Single-Blind, Controlled Trial with a 6-Month Follow-Up

Prieto-Gómez

Yuste-Sánchez

Bailón-Cerezo

et al. 2022

JCM

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“…Exercise interventions have been proven to alleviate fatigue while improving physical outcomes during and after breast cancer treatment. In a previous umbrella review of 24 systematic reviews on breast cancer and exercise, 21 studies (87.5%) reported that exercise reduced CRF and that both resistance and aerobic exercise helped to relieve fatigue symptoms in BCS [ 11 ]. Moreover, in a systematic review of randomized controlled trials (RCTs) including 36 studies, combinations of aerobic and resistance exercise showed significant associations with improved quality of life in BCS [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of fatigue and fatigability correlates in Korean breast cancer survivors and differences in associations with anxiety, depression, sleep disturbance, and endocrine symptoms: a randomized controlled trial

et al. 2021

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Background Fatigue is one of the most common and burdensome symptoms experienced by cancer patients. In interventions intended to reduce fatigue in such patients, fatigability, or perception of fatigue contextualized to activities of fixed intensity and duration, may also be measured. This study investigated the effects of a 15-month intervention on fatigue and fatigability in breast cancer survivors (BCS); explored the fatigue-fatigability relationship; and evaluated the impacts of fatigue and fatigability on anxiety, depression, sleep disturbance, and endocrine symptoms. Methods A randomized controlled trial design was applied to an exercise program called BLESS (Better Life after cancer, Energy, Strength, and Support). The intervention included this 12-week exercise program and four follow-up contacts intended to promote exercise adherence over the following year. Participants were women aged 20 to 69 who had been diagnosed with stage I, II, or III breast cancer; had completed active treatment; and had moderate or higher fatigue. At the completion of the intervention, the survey responses of 40 BCS were evaluated using the chi-square test and multiple regression analysis. The Korean versions of the Revised Piper Fatigue Scale and Pittsburgh Fatigability Scale were used to measure fatigue and fatigability, respectively. Results There was no significant difference in fatigue or fatigability between the experimental and control groups at intervention completion. However, the control group showed a stronger association than the experimental group between fatigue and physical fatigability. In the control group, fatigue and fatigability were significantly associated with anxiety, depression, sleep disturbance, and endocrine symptoms. In the experimental group, only the cognitive/mood fatigue score and depression were significantly associated. Only endocrine symptoms influenced mental fatigability (B = − 0.185, P < 0.05), and only depression influenced cognitive/mood fatigue (B = 1.469, P < 0.05). Conclusions Fatigue and fatigability showed different correlations with cancer-related symptoms after the exercise intervention. Future assessments of fatigability in intervention studies will allow measurement of the spectrum of patients’ abilities to overcome fatigue at various physical activity levels while capturing different aspects of cancer-related symptoms. Trial registration This study was retrospectively registered on Clinical Research Information Service (KCT0005763; date of registration: 31/12/2020).

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“…Contudo, pouco se sabe sobre a etiologia da fadiga relacionada ao câncer 14 . Uma recente revisão de revisões sistemáticas demonstrou que intervenções com exercícios físicos (aeróbio e força) são capazes de reduzir a percepção de fadiga de mulheres diagnosticadas com câncer de mama 15 .…”

Section: Introductionunclassified

Exercício físico remoto e fadiga em sobreviventes do câncer de mama: uma intervenção em tempos do COVID-19

Pinto

Andrade

Fonseca

et al. 2020

Rev Bras Ativ Fís Saúde

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O objetivo do presente estudo foi verificar os efeitos de um programa de exercício físico supervisionado remotamente sobre a percepção de fadiga de sobreviventes do câncer de mama durante a pandemia da COVID-19. Participaram do estudo dez mulheres (56,30 ± 14,00 anos) fisicamente ativas, participantes de um programa de extensão universitário e que foram diagnosticadas com câncer de mama entre os estágios I-III (5,65 ± 2,19 anos de diagnóstico). O programa de exercício físico foi realizado de forma supervisionada por meio de chamada de vídeo durante 12 semanas, com duas sessões semanais de 30 minutos, em dias não consecutivos. Os treinos foram compostos por exercícios de mobilidade articular, de força, aeróbios e de equilíbrio, sendo modificados a cada três semanas. A percepção de fadiga relacionada ao câncer foi medida pela Piper Fatigue Scale por meio de chamada telefônica, antes e após as 12 semanas de intervenção. Os dados foram analisados utilizando o teste não-paramétrico Wilcoxon. Os resultados demonstraram valores de todos os domínios da fadiga relacionada ao câncer (fadiga total: p = 0,463; comportamental: p = 0,655; afetiva: p = 0,593; sensorial: p = 0,223; cognitiva: p = 0,141) estatisticamente semelhantes entre os momentos pré e pós intervenção. Conclui-se que, após 12 semanas de um programa de exercício físico supervisionado remotamente por chamada de vídeo, durante o distanciamento social devido a pandemia da COVID-19, a percepção de fadiga de mulheres sobreviventes do câncer de mama permaneceu estável.

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Exercise for fatigue in breast cancer patients: An umbrella review of systematic reviews

Cited by 28 publications

References 49 publications

Effectiveness of Therapeutic Exercise and Patient Education on Cancer-Related Fatigue in Breast Cancer Survivors: A Randomised, Single-Blind, Controlled Trial with a 6-Month Follow-Up

Effectiveness of Therapeutic Exercise and Patient Education on Cancer-Related Fatigue in Breast Cancer Survivors: A Randomised, Single-Blind, Controlled Trial with a 6-Month Follow-Up

Comparison of fatigue and fatigability correlates in Korean breast cancer survivors and differences in associations with anxiety, depression, sleep disturbance, and endocrine symptoms: a randomized controlled trial

Exercício físico remoto e fadiga em sobreviventes do câncer de mama: uma intervenção em tempos do COVID-19

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