Exercise and Nutrition Interventions in Advanced Lung Cancer: A Systematic Review

Abstract

More research is required to ascertain the optimal physical activity and nutrition interventions in advanced inoperable nsclc. Specifically, the potential benefits of combining physical activity with nutrition counselling have yet to be adequately explored in this population.

Early and Intensive Dietary Counseling in Lung Cancer Patients Receiving (Chemo)Radiotherapy—A Pilot Randomized Controlled Trial

“…While the recruitment rate was relatively low, it is comparable to the rate reported in a large retrospective audit of 1043 NSCLC and SCLC patients, which investigated overall clinical trial participation in a single center over a 3-yr period, finding 43% of patients eligible for clinical trial participation refused (12). Recruitment issues and high refusal rates have previously been reported as common in supportive care trials in patients with lung cancer and need to be factored into future study design and sample size calculations (13,28). High attrition has also been reported as common in supportive care trials in lung cancer patients.…”

Combining nutrition and exercise to optimize survival and recovery from critical illness: Conceptual and methodological issues

“…For instance, in older people, exercise along with protein supplementation may promote greater rates of protein synthesis [24,25] and greater improvements in strength compared with exercise alone or nutritional supplements [26e28]. Other studies in patients with obesity [29], HIV/AIDs [30], chronic obstructive pulmonary disease [31] and healthy volunteers undergoing 60 days of bed rest [32,33] suggest that the nutritional intervention, alone, has minimal effect on muscle, but that the combination of exercise and nutritional intervention yields the greatest improvement in muscle mass and strength. In a recent meta-analysis, protein supplementation, when combined with resistance-type exercise training, enhanced gains in strength and muscle mass in both young and elderly non-critically ill adults compared with groups that did not supplement with protein [34].…”

Supervised exercise reduces cancer-related fatigue: a systematic review

“…9,10 Recent systematic reviews examining the effect of physical activity on psychological and functional outcomes have tended to study particular types of cancer instead of all cancer types, with lung and breast cancer being the most widely studied. [11][12][13] A recent Cochrane systematic review 14 about exercise and cancer-related fatigue concluded that aerobic exercise reduces cancer-related fatigue and encouraged further research of other exercise modalities; however, this review only included data published before March 2011 and did not examine supervised physical activity interventions in isolation from unsupervised interventions.…”