Exercício resistido na avaliação da disfunção endotelial na insuficiência cardíaca

Abstract

OBJECTIVETo evaluate the use of resistive exercise in the study of endothelial dysfunction in heart failure (HF) comparatively to reactive hyperemia (RH). METHODSEighteen patients with heart failure and 15 normal volunteers were submitted to intermittent handgrip exercise in a pneumatic bag, at an intensity that corresponds to 75% of the previously assessed maximum load. Patients underwent high-resolution vascular ultrasonography for brachial artery diameter and fl ow evaluation as well as cardiac output determination at rest, RH and after exercise. The systolic fl ow index in the brachial artery and cardiac index were calculated. RESULTSSystolic fl ow index increase in the brachial artery was observed after RH and physical exercise, with the latter presenting the highest increase. There was an increase in the cardiac index after the study conditions in comparison to resting conditions. CONCLUSIONResistive exercise, performed at the assessed load, increases blood fl ow more intensively than RH, constituting a physiological option for the evaluation of endothelial function in HF. KEY WORDSEndothelial dysfunction, heart failure, exercise.

Reabilitação intra-hospitalar após transplante cardíaco

“…10 Inicialmente, esse comprometimento pode se manifestar durante o exercício; e com a progressão da doença pode até ser observado em momentos de repouso. 10 Todas as alterações ocasionadas pela IC levam ao menor fluxo periférico e à piora da capacidade do exercício, devido principalmente a alterações no transporte e no consumo de oxigênio, 11 com intolerância ao exercício, maior metabolismo anaeróbio e mudanças nas fibras musculares do tipo I para tipo II.…”

Efeito anti-inflamatório do treinamento físico na insuficiência cardíaca: papel do TNF-α e da IL-10

“…It is now well established that physical training is directly related to the functional improvement of quantitative physical capacity, such as in VO 2peak , in endothelial function and consequently in the quality of life of patients with HF 11, [50][51][52] . Other variables associated with a worse prognosis, such as an improvement in sympathetic and neuro-hormonal activity and peripheral hypoxia, have also been reported as being positively modulated by physical training 53 .…”

Quantificação semiautomática da velocidade do sangue em imagens de ultrassonografia Doppler

“…Typically, a spectrum of frequencies related to the different velocities of the blood cells (Equation 1) is presented as a curve of velocity vs. time (Figure 1). This information can reveal important relationships between the frequency spectral pattern along the cardiac cycle and the presence of cardiovascular diseases (Hoskins, 1990;Yao, 2004), among other examples (Carvalho et al, 2006;Corretti et al, 2002;Lage et al, 2002). Since commercial ultrasound systems are primarily dedicated to get instantaneous data for individual patients, they have, in general, low flexibility to perform large-scale researches.…”

“…Este gráfico contém informações que podem indicar possíveis relações entre a forma espectral durante o ciclo cardíaco e a ocorrência de doenças cardiovasculares (Hoskins, 1990;Yao, 2004). Além disso, existem estudos que requerem o conhecimento da velocidade e fluxo sanguíneos para a obtenção da disfunção endotelial na insuficiência cardíaca (Carvalho et al, 2006;Corretti et al, 2002) e aqueles que visam monitorar os efeitos da administração de determinados medicamentos no sistema circulatório .…”