Exemplification of ABO Blood Groups in Patients with Diabetes Mellitus

Abstract

INTRODUCTION: Diabetes Mellitus and blood groups are interrelated. The relationship between ABO blood groups and disease susceptibility has generated a concern. The identification of a positive relationship between DM and blood groups could indicate higher susceptibility to diabetes and a negative relationship could indicate protection from diabetes. Therefore, the objective of the study was designed to exemplify ABO blood groups in Patients with Diabetes Mellitus. MATERIALS AND METHODS: The study was conducted at Ram Janaki Hospital and Swastika Health Care Hospital, Janakpurdham from September 2017 to March 2018.The record of the patients from the medicine OPD in both the hospitals was identified and relevant data were extracted. The data was recorded from the reports of the patients with confirmed DM patients attending Medicine department. RESULTS: The majority of the 579 diabetic patients were in the 40-60 year old age group. The most predominant blood group was B (251; 43.4 %), followed by AB (137; 23.7 %), O (125; 21.5 %), and A (66; 11.4 %) respectively. In comparison to male diabetics, less than half (44.1%) of female diabetics had blood group B. (42.7%). Similarly, males (13.0 %) were found to have more blood group A than females (9.8%). In diabetic individuals, the relationship between blood group and age (p=0.652) and sex (p=0.659) was shown to be insignificant. The majority of the patients (94.3%) had Rh positive blood groups, whereas the other had Rh negative blood types (5.7%). There was no correlation between blood group Rh factor and age group (p=0.817) or as well as with sex (p=0.333) among diabetic patients. CONCLUSIONS: Diabetic patients were more likely to have blood type B, while diabetics were less likely to have blood group A. It implies that diabetes is linked to ABO blood types, and that those with Group-B are more likely to develop the condition. Blood group could be a risk factor, and knowing it can aid with disease evaluation and screening.

Association of ABO Blood Groups and Obesity in Patients With Diabetes Mellitus in King Abdulaziz University Hospital

“…In contrast to our findings, previous studies in Italy and Trinidad reported a higher prevalence of the B blood group among diabetic patients [24]. It was found that B blood group was more prevalent among diabetic patients [25]. It is believed that there is a connection between blood groups and type 2 diabetes due to shared genetic and immunologic factors [26].…”

“…It accounted for 35.71% of cases, whereas in the control group, it was only 22.52%. This pattern of blood group B being more prevalent among diabetes mellitus patients has also been observed in other studies [25,32]. It is worth noting that, in the Malaysia study, this difference compared to the control group was not statistically significant.…”

Untitled

“…Our results demonstrated that diabetes has a high prevalence in patients over 50 years of age, these results corroborate a recent study that analyzed 579 diabetic patients and showed that the highest prevalence was between 40 -60 years of age [26]. The same study revealed that blood group B has the highest frequency (42%), followed by blood group AB (23%), O (21%), and A (11.4%), respectively, while in our study the highest frequency was observed in blood group O (44%), followed by groups A (27%) and B (23%) respectively [26].…”

“…Our results demonstrated that diabetes has a high prevalence in patients over 50 years of age, these results corroborate a recent study that analyzed 579 diabetic patients and showed that the highest prevalence was between 40 -60 years of age [26]. The same study revealed that blood group B has the highest frequency (42%), followed by blood group AB (23%), O (21%), and A (11.4%), respectively, while in our study the highest frequency was observed in blood group O (44%), followed by groups A (27%) and B (23%) respectively [26]. Researchers from different countries found a diverse association between ABO blood groups and DM, this can be explained by the different distribution of blood groups in the population of these countries and varies according to the population [27,28].…”