“…The average costs of patients with MUS in Germany are approximately 8 times higher than the general population and rise with increasing symptom severity. 16,23 Although somatoform disorders and MUS are frequently linked with co-morbid mental disorders, 8,24 there is controversy on whether mental co-morbidity leads to higher HCU in patients with somatoform disorders. 10,15,21,25 Being the most common co-morbidities in patients with somatoform disorders, it seems intuitive to assume that depression and anxiety would lead to a higher HCU due to the increase of symptoms present and resulting disability.…”