Excellent cosmetic result of daylight photodynamic therapy for facial flat warts in a child

Borgia, Francesco; Coppola, Marialorena; Giuffrida, Roberta; Cannavò, Serafinella Patrizia

doi:10.1016/j.pdpdt.2019.02.021

Cited by 16 publications

(9 citation statements)

References 5 publications

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“…PDT should be considered a useful option in treatment of flat warts, particularly in aesthetically sensitive areas such as the face of children ( Borgia et al, 2020a ). Overall 31 pediatric patients with flat viral warts were treated with C-PDT or DL-PDT, achieving complete response in one case ( Borgia et al, 2019 ) and various degree of complete response ranging from 73.3% (C-PDT) to 80% (DL-PDT) in a study involving 30 patients ( Borgia et al, 2020a ).…”

Section: Pdt and Pediatric Infectious Skin Diseasesmentioning

confidence: 99%

Photodynamic therapy in pediatric age: Current applications and future trends

et al. 2022

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Photodynamic therapy (PDT) is a photochemotherapy based on local application of a photosensitive compound and subsequent exposure to a light source of adequate wavelength. It is a non-invasive therapeutic procedure widely used in oncodermatology for treatment of numerous skin cancers, but in the last years its use has been gradually extended to an increasing list of skin diseases of both infectious and inflammatory nature. Although PDT is proven as a safe and effective therapeutic option in adults, its use is not well standardized in the pediatric population. In this review, we will focus on clinical applications, mechanisms of action, protocols, and adverse events in children and adolescents. Most of pediatric experiences concerned treatment of skin cancers in Gorlin syndrome and xeroderma pigmentosum, acne vulgaris, and viral warts, but other applications emerged, such as cutaneous lymphoma and pseudo-lymphomas, necrobiosis lipoidica, hidradenitis suppurativa, dissecting cellulitis, leishmaniasis, angiofibromas, verrucous epidermal nevus, and linear porokeratosis. In these pediatric diseases, PDT appeared as an effective therapeutic alternative. The results on vitiligo were limited and not fully encouraging. Although highly versatile, PDT is not a therapy for all skin diseases, and a deeper knowledge of its mechanisms of action is required to better define its spectrum of action and safety in pediatric patients.

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Section: Pdt and Pediatric Infectious Skin Diseasesmentioning

confidence: 99%

Photodynamic therapy in pediatric age: Current applications and future trends

et al. 2022

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“…Dear Editor, Cutaneous viral warts (VWs) are lesions caused by Human Papillomavirus (HPV), commonly found in children. 1…”

Section: Successful Photodynamic Therapy In a Pediatric Patient With mentioning

confidence: 99%

“…Dear Editor, Cutaneous viral warts (VWs) are lesions caused by Human Papillomavirus (HPV), commonly found in children. 1 Several therapies are employed for the treatment of warts (topical keratolytics, electrosurgery, cryotherapy, laser ablation), although often complicated by pain, scars, hyper−/hypopigmentation and high risk of recurrence. 1 Conventional photodynamic therapy (PDT) involves the use of a topical photosensitizer and a red-light to generate reactive oxygen species.…”

Section: Successful Photodynamic Therapy In a Pediatric Patient With mentioning

confidence: 99%

“…1 Several therapies are employed for the treatment of warts (topical keratolytics, electrosurgery, cryotherapy, laser ablation), although often complicated by pain, scars, hyper−/hypopigmentation and high risk of recurrence. 1 Conventional photodynamic therapy (PDT) involves the use of a topical photosensitizer and a red-light to generate reactive oxygen species. It has shown encouraging results in the treatment of VWs, being able to be used in extensive areas of affected skin and showing superior cosmetic results compared with other treatments.…”

Section: Successful Photodynamic Therapy In a Pediatric Patient With mentioning

confidence: 99%

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Successful photodynamic therapy in a pediatric patient with difficult warts

Borgia

Giuffrida

Coppola

et al. 2020

Dermatologic Therapy

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Many clinical studies reported the safety and efficacy of PDT in the treatment of VWs. Chong and Kang reported complete healing of a recalcitrant acral VW after three PDT sessions. 5 Recently, Huang et al. reported that, compared with cryotherapy, the combination of superficial shaving and PDT results in a better healing and a lower recurrence rate of warts. 4 In our case, clearance of warts was achieved after only two sessions, with minimal side effects and no recurrence at one-year follow-up. In conclusion, PDT may represent a relatively new therapeutic modality for some patients with warts, especially where other treatments have shown no or minimal improvement, or in whom invasive therapies should be avoided or not well tolerated.

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“…6 In this study, we confirm the high efficacy and safety of C-PDT with 5-ALA in the pediatric setting. 4,7,8 An otherwise healthy 5-year-old female was brought to our attention by her parents for a 30-months history of multiple skin-colored, verrucous papules in the perineal area (Figure 1A). She had been previously visited by many physicians (both pediatricians and dermatologists) with a diagnosis of GWs, and treated with imiquimod 5% cream and cryotherapy, which were ineffective, and poor tolerated by the patient.…”

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Photodynamic therapy for pediatric genital warts: A case report

Macca

Pomi

Custurone

et al. 2022

Dermatologic Therapy

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Genital warts (GWs) are the most common sexually transmitted infections (STIs), caused by the human papillomavirus. 1 The most common way of infection in adults is sexual, but transmission in pediatric populations remains controversial. 2 The increasing prevalence of GWs in children, ranged from 0% to 80%, 3 has renewed the interest in understanding the social and legal impact in cases of sexual abuse. In addition to concerns regarding the potential abuse, treatment for GWs in pediatric populations also present a unique challenge. Many variables influence the treatment eligibility, such as the size, quantity, and location of the warts. 4 Invasive treatments (surgical excision, cryotherapy, carbon dioxide laser, and electrocoagulation) are painful

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Excellent cosmetic result of daylight photodynamic therapy for facial flat warts in a child

Cited by 16 publications

References 5 publications

Photodynamic therapy in pediatric age: Current applications and future trends

Photodynamic therapy in pediatric age: Current applications and future trends

Successful photodynamic therapy in a pediatric patient with difficult warts

Photodynamic therapy for pediatric genital warts: A case report

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