Examining Antibiotic Use at an Education and Research Hospital in Turkey: Point Prevalence Results

Yilmaz, Gül Ruhsar; Bulut, Cemal; Yildiz, Fatih; Arslan, Selcan; Yetkin, Meltem Arzu; Demiröz, Ali Pekcan

doi:10.3906/sag-0802-33

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…In Pakistan, Nigeria and Tanzania, higher rates of antibiotic use were reported ranging from 62% to 80.1% [ 31 – 33 ]. While the rate of antibiotic use in our study was similar to previous studies in our country [ 7 , 28 , 29 ], it was observed with a higher rate than some of the European countries, it is observed lower than in Asia and some European countries [ 14 , 32 , 34 ].…”

Section: Discussionsupporting

confidence: 89%

“…In our study, the rate of inappropriate use was 20% and was quite lower than previous studies. In the previous studies, rates of inappropriateness varied between 25.8% and 54.3% from our country [ 28 – 30 ]. Ingram et al reported 47% inappropriate antibiotic usage [ 5 ].…”

Section: Discussionmentioning

confidence: 80%

“…In present study, 33.8% of hospitalized adult patients were using at least one antibiotic. In previous studies from our country, the antibiotic prescription was reported at different rates varying from 27.2% to 44.8% [15,[27][28][29][30]. In a study from Australia, a rate of 43% antibiotic use was reported, while in a multicenter study including 13 centers in China, this rate was reported as 56% [5,14] In a study evaluating antibiotic use in 53 countries in Europe, rates of antibiotic use were reported as 15.6% in Northern Europe and 43.9% in Eastern Europe.…”

Section: Discussionmentioning

confidence: 93%

“…The most effective and feasible way to control the spread of multi-drug resistant microorganisms is to provide rational antibiotic use [ 28 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

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Point prevalence of antibiotic usage in major referral hospital in Turkey

Ayhan,

Coşkun,

Kayaaslan

et al. 2024

PLoS ONE

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Introduction The most important and undesirable consequence of inappropriate antibiotic use is the spread of antibiotic resistance, increased adverse effects, increased mortality and healthcare costs. We aimed to assess antibiotic usage characteristics in inpatient setting in our center. Materials and methods A one-day, single center point-prevalence study was carried out on June 9th 2021, in Ankara City Hospital in Turkey. Data of antibiotic consumption, appropriateness of usage and predictors of inappropriate use in adult patients were evaluated. Results Out of 2640 adult patients, 893 (33.8%) were receiving at least one antibiotic. A total of 1212 antibiotic prescriptions with an average of 1.44±0.64 were found. Antibiotics were most commonly used for therapeutic purpose (84.7%), followed by surgical prophylaxis (11.6%). Majority of therapeutically used antibiotics were empirical (67.9%). Infectious diseases consultation was present in 68.3% with a compliance rate of 95.7%. Rate of inappropriate use was 20%. The most frequent cause of inappropriateness was unnecessary use (52.5%). Most commonly and most inappropriately used antibiotics were carbapenems (17.5%) and first generation cephalosporins (38.7%), respectively. Most of the inappropriateness observed in first-generation cephalosporins was due to inappropriate longer surgical prophylaxis. While age is an independent risk factor for inappropriate antibiotic use (p = 0.042), COVID-19 unit admission, use for therapeutic purpose and infectious diseases consultation were protective factors (p<0.001, p<0.001, p<0.001). Conclusion Rate of inappropriate use was low, but inappropriate surgical prophylaxis remains an important problem in surgical units. There is a considerable need to implement an antimicrobial stewardship program that focuses on surgical prophylaxis practices.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 93%

“…The most effective and feasible way to control the spread of multi-drug resistant microorganisms is to provide rational antibiotic use [ 28 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Point prevalence of antibiotic usage in major referral hospital in Turkey

Ayhan,

Coşkun,

Kayaaslan

et al. 2024

PLoS ONE

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P092: Antibiotic usage and appropriateness for a university hospital in Turkey: point prevalence results

Gül¹,

Karakaş²,

Artuk³

et al. 2013

Antimicrob Resist Infect Control

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Kirikkale İli̇ndeki̇ İki̇ Hastanede Yatan Hastalarda Anti̇bi̇yoti̇k Kullanimi: Bi̇r Günlük Nokta Prevalans Çalişmasi

Öztürk¹,

Kaçmaz

Edis³

et al. 2019

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

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Amaç: Antibiyotikler, dünyada en fazla kullanılan ilaçlar arasındadır. Antibiyotiklerin endikasyon dışı ve bilinçsizce kullanımı hem mikroorganizmaların direnç geliştirmesine hem de ekonomik yüke neden olabilir. Bu çalışmada Kırıkkale İlindeki iki hastanede yatan hastaların antibiyotik kullanımları ve uygunsuz antibiyotik kullanım oranları araştırılmıştır. Gereç ve Yöntem: Çalışma; Kırıkkale ilinde, biri devlet, diğeri üniversiteye bağlı iki büyük hastanede nokta prevalans metoduyla yapılmıştır. Çalışmanın yapıldığı gün hastanelerin doluluk oranı, yatan hasta sayısı, kullanılan antibiyotikler kayıt altına alındı. Hastaların antibiyotik kullanımlarının uygun endikasyonda olup olmadığı çalışma grubunda yer alan enfeksiyon hastalıkları uzmanlarınca değerlendirildi. İstatistiksel ölçümler için SPSS 15.0 programı kullanıldı. Bulgular: İki hastanede toplam 443 hasta yatıyordu ve bunların 221’i antibiyotik tedavisi alıyordu. Hastaların, %92.8’sine antibiyotik tedavisi ampirik olarak başlanmışken, %7.2’si kültür sonuçlarına göre başlanmıştı. Antibiyotik kullanan hastaların 137’sinde (%61.9) antibiyotik kullanımı uygundu. Antibiyotikler, çoğunlukla tedavi amaçlı başlanmıştı. Profilaktik amaçlı tedavi alan hastaların %19.1’ine uygun proflaksi yapılmışken, tedavi amaçlı antibiyotik alan hastaların %73.5’i uygun antibiyotik tedavisi almıştı ve fark istatistiksel olarak anlamlıydı (p<0.001). Enfeksiyon hastalıkları konsültasyonu yalnızca 53 hastadan istenmişti ve konsültasyon istenmesi antibiyotik kullanımında uygunluk oranını arttırmıştı. Cerrahi klinikler en çok uygunsuz antibiyotik kullanan kliniklerdi.Sonuç: Antibiyotik tedavisine başlanılmadan önce, enfeksiyon hastalıkları uzmanından görüş alınmasının önemli olduğunu düşünüyoruz.

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Examining Antibiotic Use at an Education and Research Hospital in Turkey: Point Prevalence Results

Cited by 6 publications

References 22 publications

Point prevalence of antibiotic usage in major referral hospital in Turkey

Point prevalence of antibiotic usage in major referral hospital in Turkey

P092: Antibiotic usage and appropriateness for a university hospital in Turkey: point prevalence results

Kirikkale İli̇ndeki̇ İki̇ Hastanede Yatan Hastalarda Anti̇bi̇yoti̇k Kullanimi: Bi̇r Günlük Nokta Prevalans Çalişmasi

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