Examination of Disinfectants

Reddish, George F.

doi:10.2105/ajph.17.4.320

Cited by 27 publications

(5 citation statements)

References 2 publications

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“…With the exception of Mycobacterium tuberculosis, all other organisms such as Salmonella typhosa, Corynebacterium diphtheriae, Diplococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus pyogenes var. aureus were used in the tests as recommended by Reddish (8)(9)(10)(11)(12). In all the cases, simultaneous tests on the same broth cultures were run with different dilutions of phenol to assess the phenol resistance of the organisms.…”

Section: Methodsmentioning

confidence: 99%

Combined Effects of Diphenyliodonium Chloride, Pine Oils, and Mustard Oil Soaps on Certain Microorganisms

Ahmed

Siddiqui

Khan

1969

Applied Microbiology

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Bactericidal and bacteriostatic activities of an emulsion containing 10.0% (v/v) terpineol, 0.5% (w/v) diphenyliodonium chloride, 11.0% (v/v) ethyl alcohol, and 5.62% saponified mustard oil were tested against a number of different types of organisms. The bactericidal concentration for Salmonella typhosa was 1:400. In the presence of 5.0% horse serum, it increased to 1:250. The bacteriostatic concentration varied from organism to organism; Escherichia coil and Staphylococcus aureus required 4,000 ,g/ml for complete bacteriostasis, whereas Corynebacterium diphtheriae, Salmonella paratyphi-A, and Shigella required only 2,000 Ag/ml for complete inhibition. A 4.0% concentration of the emulsion killed the spores of Bacillus subtilis within 6 hr.

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Section: Methodsmentioning

confidence: 99%

Combined Effects of Diphenyliodonium Chloride, Pine Oils, and Mustard Oil Soaps on Certain Microorganisms

Ahmed

Siddiqui

Khan

1969

Applied Microbiology

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“…Direct measurement of bactericidal value In order to judge the efficiency of the manometric method, parallel bactericidal tests were conducted by the method of the F. D. A. (Ruehle and Brewer, 1931) described by Reddish (1927), except that E. coli was used as the test organism. To make the comparison more exact, we have carried out at the same time modified tests in which the numbers of bacteria, time of exposure, and composition of the medium were so adjusted as to duplicate the conditions obtaining in the manometric tests.…”

Section: Methodsmentioning

confidence: 99%

“…Various dilutions of each of the disinfectants were made in 8The strain of E. coli used here was killed at 370C. under the standard conditions (Reddish, 1927) broth, and 10 ml. of each dilution were seeded with a 4-mm.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of Germicides by a Manometric Method.

Bronfenbrenner

Hershey

Doubly

1938

Experimental Biology and Medicine

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other feathers (Greenwood and Blyth,' Parkes and Selye"). These changes, taken in connection with the effects of hyperthyroidism reported here, suggest a relative increase in extent of the ventral field of saddle feathers grown under conditions of hypothyroidism. The appearance in the breast tracts of longer, saddle-like feathers with restricted barbulation following thyroidectomy is in all probability likewise associated (among other germinal changes) with a ventral field of greater or lesser extent. It should be a matter of considerable interest to alter experimentally the balance of other hormones in thyroidectomized birds in order to test the specificity of thyroxin in determining and maintaining the limited ventral triangle of feather germs of different tracts. PThe need for a method capable of evaluating germicides for chemotherapeutic use is universally recognized. Obviously, the first requirement is that the method should simulate as nearly as possible the conditions met in the animal body. In addition it should be relatively simple and should yield information regarding the action of the test substance on bacteria, and on animal tissues, in terms which would permit a direct comparison of the respective effects. The method of Lambert,' employed more recently by Salle,2 does not seem to fulfill these requirements, since the parasitotropic and organotropic properties of the disinfectant are tested under profoundly different conditions. Moreover, it is based on a tissue-culture technic which is time consuming and laborious.The manometric method proposed here has proved simple, rapid, and remarkably flexible. It permits the conditions of testing to be modified at will, and at the same time allows wide latitude in the 5Greenwood,

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“…The results are tabulated in tables 5 and 6. (table 7) the phenol coefficients were calculated in accordance with the method formulated by Reddish (1927) Dilution of X which will kill in 10 minutes but not in 5 minutes Phenol Coefficient =Diuonf Dilution of phenol which will kill in 10 minutes but not in 5 minutes…”

Section: Methodsmentioning

confidence: 99%

The Influence of Certain Inorganic Salts on the Germicidal Activity of Hydrogen Peroxide

1930

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Several investigators have noted during recent years that the decomposition of hydrogen peroxide is accelerated by the presence of certain inorganic salts. The results of earlier investigations have been sutmmarized by Bohnson (1921) who studied the mechanism of the decomposition of hydrogen peroxide by ferric salts, and noted that ethyl alcohol was oxidized to acetic acid by hydrogen peroxide in the presence of a ferric salt, a reaction which was quantitatively studied by Walton and Christensen (1926). Walton and Graham (1928) in a study of the oxidation of certain dicarboxylic acids showed that ferric or cupric salts increased the oxidizing power of hydrogen peroxide. Promoter action' in the catalytic decomposition of hydrogen peroxide has been extensively studied by Professor J. H. Walton and his students. Bohnson and Robertson (1923) and Robertson (1925) studied the promotor effect of cupric salts on the decomposition of hydrogen peroxide catalyzed by ferric salts. Robertson (1926Robertson ( , 1927 showed that the decomposition of hydrogen peroxide catalyzed by potassium dichromate was promoted by cobaltous or manganous salts. Walton and Graham (unpublished data) found that the oxidation of hydrazine by hydrogen peroxide was accelerated by both cupric and ferric ions, and that the cupric ions promoted the oxidation catalyzed by the ferric ions.The germicidal activity of hydrogen peroxide is apparently 1 A promoter in the broadest sense is a substance whose presence in relatively small amount increases the activity of a catalyst. 203 on July 16, 2020 by guest

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Examination of Disinfectants

Cited by 27 publications

References 2 publications

Combined Effects of Diphenyliodonium Chloride, Pine Oils, and Mustard Oil Soaps on Certain Microorganisms

Combined Effects of Diphenyliodonium Chloride, Pine Oils, and Mustard Oil Soaps on Certain Microorganisms

Evaluation of Germicides by a Manometric Method.

The Influence of Certain Inorganic Salts on the Germicidal Activity of Hydrogen Peroxide

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