Evoked Potentials in Geriatric Depression

Subchronic hydrocortisone treatment alters auditory evoked potentials in normal subjects

“…Some authors report a decrease in P 300 amplitude which increases on clinical recovery, but no change in P 300 latency, compared with controls (Pfefferbaum et al 1984(Pfefferbaum et al , 1985Blackwood et al 1987;Muir et al 1991;Gangadhar et al 1993;Hansenne et al 1994;Yanai et al 1997). However, Hendrikson et al (1979, Kalayam (1997) and Vandoolaeghe et al (1998) reported an increase in P 300 latency in non-demented depressed patients. Dahabra et al (1998) found prolonged auditory P 300 latencies but no change in amplitude in elderly patients who were clinically recovered from depression compared with age-matched controls.…”