Evidências do impacto da suplementação múltipla com micronutrientes no crescimento de pré-escolares: revisão sistemática

Pedraza, Dixis Figueroa

doi:10.1590/s1519-38292014000100002

Cited by 6 publications

(3 citation statements)

References 49 publications

(183 reference statements)

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“…It must be considered that the supplementation offered to these children are in accordance with the recommendation of the Brazilian Ministry of Health, which proposes higher dose (200,000 IU) only after 12 months of age and up to 59 months, 6 months spacing 12 . According to Lima et al 28 , vitamin A supplementation in the period of childhood is given as a public health strategy to improve child survival and reduce the risk of morbidity from infectious diseases 28 , as this age group is among the most vulnerable to the develop vitamin A deficiency 33,34 . However, the effectiveness of this supplementation in this age group must be studied, as in this review only two studies addressed supplementation in children.…”

Section: Discussionmentioning

confidence: 99%

Efect of vitamin A suplementation: a systematic review

Soares

Silva

Garcia³

et al. 2019

Ciênc. saúde coletiva

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To evaluate the effect of vitamin A supplementation in postpartum infants and women on serum retinol levels and breast milk. The databases Medline, PubMed, Lilacs and SciELO were consulted. The descriptors used were vitamin A, dietary supplement, child, postpartum period, infant and nutrition programs policies. Search found 7432 articles. After elimination of duplicity and application of eligibility criteria, 8 studies remained. All evaluated the effect of vitamin A supplementation on immediate postpartum, five studies used retinyl palmitate supplementation, one with retinyl palmitate and two did not specify the form of supplementation. Six studies evaluated colostrum and two included supplementation of children. It was found that supplementation in the puerperium increases the concentrations of serum retinol and breast milk, however, this result was in the short term and was relevant when the previous concentrations of the mother were low. When maternal serum concentrations are adequate, the retinol content in milk does not change, with little relevance for children. Further studies should be performed to evaluate the effect of megadoses supplementation on serum concentrations of children.

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Section: Discussionmentioning

confidence: 99%

Efect of vitamin A suplementation: a systematic review

Soares

Silva

Garcia³

et al. 2019

Ciênc. saúde coletiva

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“…It acts on the maintenance of epithelial tissue, protein synthesis, differentiation of bone cells, adequate functioning of the immune system, important for the secretion and proliferation of lymphocytes [15].…”

Section: Functions Of Vitamin 'A'mentioning

confidence: 99%

“…It influences the hormonal regulation of cell division, especially via growth hormone (GH) and insulin-dependent growth factor I (IGF-I), besides interfering with mitogenic hormones, acting on cell proliferation [20].…”

Section: Zinc Functionsmentioning

confidence: 99%

Hypothetical Function of Influent Nutrients for the Immunological System in the Aspect of the Treatment of Patients with Visceral Leishmaniasis

Silva¹

2019

International Journal of New Technology and Research

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The advances in studies related to serious diseases constitute new paradigms to understand the processes of illness and seek other ways to reduce the morbidity and mortality of people affected, so this study proposes to seek new knowledge about the relationship between nutrients as an influent factor in the immune system related to the treatment of patients with visceral leishmaniasis. The nutritional factor can act effectively in the treatment during the infectious diseases, improving the recovery and the healing process. Of the various existing nutrients we searched for vitamin A, zinc and protein. Of the various functions of these nutrients it is pointed out: vitamin Astrengthening of the immune system and antioxidant defense, is fundamental for T cell growth and function, important for lymphocyte secretion and proliferation, cell differentiation, immunity mechanisms, hematopoiesis and coagulation system. Zinc, which regulates the function and expression of transporters of divalent metal-1-DMT1 and iron-IREG23-regulated mRNA, required for cell reproduction, differentiation and growth, tissue repair and immune defense, plays an important role in process of DNA transcription, translation and replication. Proteins present immunological protection, recognize and bind with antigens, such as viruses and bacteria, are enzyme catalysts, carriers of hemoglobin and myoglobin, protective of antibodies, fibrinogen and cytokines.

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Isolated and combined prevalence of anemia, vitamin A deficiency and zinc deficiency in preschool children 12-72 months for the government of Paraíba

Pedraza

Sales

2014

Rev. Nutr.

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OBJECTIVE: To estimate the isolated and combined prevalence of anemia, vitamin A deficiency and zinc deficiency in pre-school children, as well as the distribution of isolated deficiencies according to gender, age and prior supplementation with vitamin A. METHODS: Cross-sectional study with pre-school children in the state of Paraíba, Brazil. Analysis of the average concentrations of hemoglobin, serum retinol and serum zinc, according to gender, age and previous vitamin A supplementation of children were carried out as well as the risk of simultaneous occurrence of micronutrient deficiencies in the presence of these deficiencies. RESULTS: The prevalence of anemia, vitamin A deficiency and zinc deficiency were 15.4%, 23.3% and 13.8%, respectively. The anemia was significantly associated with age (p<0.01). Children previously supplemented by vitamin A had higher serum retinol concentrations than children without supplements, an effect that was not observed for concentrations of hemoglobin or serum zinc. The prevalence of anemia associated with vitamin A deficiency was 5.8%, with the chance of vitamin A deficiency and anemia coexist 2.21 times (95%CI=1.03-4.84) higher in the case of vitamin A deficiency or anemia rather than in the absence of these conditions. CONCLUSION: The high prevalence of micronutrient deficiencies which are important in child growth, as well as the coexistence of nutritional deficiencies, point out the need to strengthen nutrition intervention strategies that consider this issue.

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Evidências do impacto da suplementação múltipla com micronutrientes no crescimento de pré-escolares: revisão sistemática

Cited by 6 publications

References 49 publications

Efect of vitamin A suplementation: a systematic review

Efect of vitamin A suplementation: a systematic review

Hypothetical Function of Influent Nutrients for the Immunological System in the Aspect of the Treatment of Patients with Visceral Leishmaniasis

Isolated and combined prevalence of anemia, vitamin A deficiency and zinc deficiency in preschool children 12-72 months for the government of Paraíba

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