Evidence for the Use of Nutritional Supplements and Herbal Medicines in Common Eye Diseases

West, Adrienne L.; Oren, Gale A.; Moroi, Sayoko E.

doi:10.1016/j.ajo.2005.07.033

Cited by 55 publications

(38 citation statements)

References 76 publications

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“…However, the available evidence does not support the use of alternative medicines such as vitamins for glaucoma treatment [43,44]. Previous study reported improvement in visual fields in patients with normal-tension glaucoma after 4 weeks of treatment with oral Ginkgo biloba [45].…”

Section: Discussionmentioning

confidence: 98%

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Reduced-serum vitamin C and increased uric acid levels in normal-tension glaucoma

Yuki

Doğru

Kimura

et al. 2009

Graefes Arch Clin Exp Ophthalmol

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Section: Discussionmentioning

confidence: 98%

“…Complementary and alternative medicines such as multivitamins are used in the treatment of age-related macular degeneration and cataract [43]. However, the available evidence does not support the use of alternative medicines such as vitamins for glaucoma treatment [43,44].…”

Section: Discussionmentioning

confidence: 99%

Reduced-serum vitamin C and increased uric acid levels in normal-tension glaucoma

Yuki

Doğru

Kimura

et al. 2009

Graefes Arch Clin Exp Ophthalmol

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“…Among the different fundamental dietary elements, the role of lipids and essential fatty acids seems particularly interesting [42] . Published studies and information found in PubMed, International Bibliographic Information of dietary supplements and selected websites have been reviewed by West et al [43] for the role of nutritional and herbal medicines in the treatment of AMD, cataract, diabetic retinopathy and glaucoma. The available evidence does support the use of certain vitamins and minerals in patients with certain forms of AMD.…”

Section: Dietary Interventions As Strategy For Prevention Of Other Ocmentioning

confidence: 99%

The Importance of Nutrition in the Prevention of Ocular Disease with Special Reference to Cataract

Agte

Tarwadi

2010

Ophthalmic Res

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Background: The lens is the ocular structure most susceptible to oxidative damage. Antioxidants, micronutrients and phytochemicals have been extensively studied for their possible effects to prevent or delay the progression of various eye diseases. Objectives: A brief overview of the updated literature on the role of antioxidants and micronutrients in the prevention and treatment of ocular diseases is to be presented with an emphasis on cataract. Data Sources: PubMed search and individual papers from journals. Data Synthesis: The review discusses linkages of various micronutrients and antioxidants as well as oxidative stress with cataract. Dietary interventions as strategy for prevention of cataract and other ocular disorders are also reviewed. Conclusions: Consumption of food-based antioxidants like β-carotene lutein and zeaxanthin seem to be useful for the treatment of macular degeneration and cataracts. Supplements of vitamin A, vitamin C, vitamin E and zinc may prevent advanced age-related macular degeneration only in high-risk individuals.

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“…The practice of utilizing plant-based products to aid in the overall health status of an individual has been commonplace for thousands of year [1][2][3][4]. Specifically, herbal supplementation is thought to potentially remedy a large range of ailments and/or diseases such as diabetes [5], cardiovascular disease [6,7], chronic liver disease [8,9], eye diseases [10], and prostate disease [11,12]. The use of herbal products worldwide has experienced exponential growth since the 1970's.…”

Section: Overview Of Herbal Dietary Supplementsmentioning

confidence: 99%

“…Recent estimates indicate that approximately half (49%) of all US adults partake in some form of dietary supplementation [13], often involving herbal products. Investigations have been conducted on the effectiveness of herbal supplementation over a wide range of applications including: pregnancy [14], obesity [15], depression [16], and physical performance [17], as well as involving herbal supplementation to treat various diseases [8,10,11,18].…”

Section: Overview Of Herbal Dietary Supplementsmentioning

confidence: 99%

Increasing Circulating Testosterone: Impact of Herbal Dietary Supplements

Gunnels¹

2014

J Plant Biochem Physiol

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Low circulating testosterone levels can present numerous problems related to the overall health and well-being of individuals, men in particular. This finding is well-documented in the literature and low testosterone appears more prevalent in older men, in particular those who are physically inactive and who present with elevated levels of body fat. Multiple botanical (herbal) products have been claimed to elevate circulating testosterone in men; however, data pertaining to the use of such herbal preparations obtained from human clinical trials are limited. This review examines the research to date pertaining to the use of herbal ingredients with regards to their ability to elevate blood testosterone levels. A collective summary of the findings indicate that certain herbal supplements may actually yield an increase in testosterone (e.g., Longjack root), while most others have little to no evidence in support of their use in human subjects. Additional, well-controlled clinical trials are needed to generate data relative to the use of herbal dietary supplements to increase circulating testosterone. Testosterone is generally measured as either "free" (unbound) or "total" (unbound and chemically bound). Men who have a morning serum testosterone level < 300 ng/dL are considered to be "low" and may be a candidate for testosterone replacement therapy-which has become more common in recent years due to the increased diagnosis of andropause [55]. Insufficient levels of testosterone due to either impaired production or uptake can present serious health consequences due to the wide array of applications of testosterone within the human body. Areas including skeletal muscle health, muscular strength, and overall well-being/vitality seem to be significantly affected by testosterone status. Increasing Circulating Testosterone: Impact of Herbal Dietary SupplementsTrintThe role of testosterone in muscle growth has been investigated extensively in both humans and animals [56][57][58][59][60][61][62]. One study in men concluded that the testosterone-induced increase in muscle volume is due to muscle fiber hypertrophy [63]. A follow-up study conducted a year later noted muscle hypertrophy in men over a period of 20 weeks of treatment with a gonadotropin-releasing hormone agonist and a 125-, 300-, or 600-mg weekly dose of testosterone enanthate. The main findings from this study indicated that testosterone administration was associated with a significant increase in myonuclear number in men receiving the 300-and 600-mg doses.Muscular strength is another important factor that has been shown to be affected by testosterone levels in the body [56,61,62,[64][65][66]. A recent investigation utilized 267 men with stages 2-4 of Chronic Kidney Disease to assess the impact of testosterone level on a variety of variables [64]. This study found that testosterone was significantly and independently associated with handgrip strength, muscle mass, and nutritional status as the disease progressed. Another study explored short-term testoste...

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Evidence for the Use of Nutritional Supplements and Herbal Medicines in Common Eye Diseases

Cited by 55 publications

References 76 publications

Reduced-serum vitamin C and increased uric acid levels in normal-tension glaucoma

Reduced-serum vitamin C and increased uric acid levels in normal-tension glaucoma

The Importance of Nutrition in the Prevention of Ocular Disease with Special Reference to Cataract

Increasing Circulating Testosterone: Impact of Herbal Dietary Supplements

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