“…Heulin et al [13] in our laboratory found that human serum :ontained factors with molecular weights (MWs) below 1000 "Corresponding author. Fax: (33) (83) 85.11.88.…”
Human plasma has been shown to contain a low molecular weight factor that potentiates human IGF-I stimulation of glycosaminoglycan synthesis in chick embryo cartilage. The peptide was purified and characterized by Edman degradation and electrospray mass spectrometry. The primary structure determined was: Trp-Gly-His-Glu. A homologous synthetic peptide similarly promoted matrix biosynthesis in cartilage exposed to
“…Heulin et al [13] in our laboratory found that human serum :ontained factors with molecular weights (MWs) below 1000 "Corresponding author. Fax: (33) (83) 85.11.88.…”
Human plasma has been shown to contain a low molecular weight factor that potentiates human IGF-I stimulation of glycosaminoglycan synthesis in chick embryo cartilage. The peptide was purified and characterized by Edman degradation and electrospray mass spectrometry. The primary structure determined was: Trp-Gly-His-Glu. A homologous synthetic peptide similarly promoted matrix biosynthesis in cartilage exposed to
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