Evariquinone, isoemericellin, and stromemycin from a sponge derived strain of the fungus Emericella variecolor

Bringmann, Gerhard; Lang, Gerhard K.; Steffens, S.; Günther, E; Schaumann, K.

doi:10.1016/s0031-9422(03)00189-4

Cited by 71 publications

(64 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The occurrence of prenylated xanthones is restricted to the plant species of the family Guttiferae. The major C 5 unit of the substituents included the commonly found 3-methylbut-2-enyl or isoprenyl group as in isoemericellin and the less frequent 3-hydroxy-3-methylbutyl as in nigrolineaxanthone P and 1,1-dimethylprop-2-enyl as in globuxanthone, respectively [35][36][37]. Prenylated xanthones, caloxanthone O and caloxanthone P, were isolated from Calophyllum inophyllum [38] and polyprenylated xanthones and benzophenones from Garcinia oblongifolia [39].…”

Section: Prenylated and Related Xanthonesmentioning

confidence: 99%

Naturally Occurring Xanthones: Chemistry and Biology

Negi

Bisht

Singh

et al. 2013

Journal of Applied Chemistry

164

120

View full text Add to dashboard Cite

Xanthones are one of the biggest classes of compounds in natural product chemistry. A number of xanthones have been isolated from natural sources of higher plants, fungi, ferns, and lichens. They have gradually risen to great importance because of their medicinal properties. This review focuses on the types, isolation, characterization, biological applications, and biosynthesis of naturally occurring xanthones isolated so far. Different physicochemical and instrumental methods such as liquid-solid and liquid-liquid extraction, TLC, flash chromatography, column chromatography, IR,1H NMR and13C NMR spectroscopy, GLC, HPLC, GC, and LCMS have been widely used for isolation and structural elucidation of xanthones. Hepatoprotective, anticarcinogenic, antileprosy, antimalarial, antioxidant, anticholinergic, mutagenicity, radioprotective, immunomodulatory, antibone resorption, antiparasitic, neuraminidase inhibitory, anticomplement, antibacterial, antifungal, algicidal, anti-HIV, cardioprotective, antitumoral, antidiabetes, antihyperlipidemic, antiatherogenic, anti-inflammatory, antiulcer, antidiabetic, hypolipidemic, analgesic, antiasthmatic, antihistaminic, antiamoebic, diuretic, antidiarrheal, larvicidal, and ovicidal activities have been reported for natural occurring xanthones. To a certain extent, this review provides necessary foundation for further research and development of new medicines.

show abstract

Section: Prenylated and Related Xanthonesmentioning

confidence: 99%

Naturally Occurring Xanthones: Chemistry and Biology

Negi

Bisht

Singh

et al. 2013

Journal of Applied Chemistry

164

120

View full text Add to dashboard Cite

show abstract

“…C-glycosides are fewer in number as compare to O-glycosides. For example, mangiferin (22) and isomangiferin are most common C-glycosides, and Swertia japonica (24) and gentioside are few O-glycosides.…”

Section: Xanthone Glycosidesmentioning

confidence: 99%

“…These are the xanthones in which 5-carbon unit such as isoprenyl and 1,1-dimethylprop-2-enyl,3-hydroxy-3-methylbutyl [24][25][26] is attached as a substituent to xanthone nucleus, for example,…”

Section: Prenylated Xanthonementioning

confidence: 99%

Synthesis and Biological Properties of Pharmaceutically Important Xanthones and Benzoxanthone Analogs: A Brief Review.

Bedi

Gupta

Pramanik

2018

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Xanthones are one of the biggest classes of compounds in natural product chemistry. A number of xanthones have been isolated from natural sources of higher plants such as fungi, ferns, and lichens. Synthetic analogs of xanthones have shown a large number of pharmacological properties such as antioxidant, anti-inflammatory, antidiabetics, antihistamine, antitumoral, antiulcer, and algicidal. Moreover, they also find usages in photodynamic therapy, laser technology, and dyes. This review lays stress on various solvents, catalyst and synthetic route for synthesis of xanthones, benzoxanthones analogs. The review has also focused on the classifications of xanthone as well as extensively studied biological properties of the xanthones and benzoxanthones analogs.

show abstract

“…[63,64] (Figure 7.24). Since then, other bioactive compounds have been isolated and characterized ( 1 H, 13 C, COSY, ROESY, and one-bond and long-range heteronuclear correlations) from fungal isolates derived from marine sponges using this online stop-flow approach [65,66].…”

Section: Hyphenated Nmr Techniquesmentioning

confidence: 99%