Evaluation of Using Mineralized Plasmatic Matrix in Osseous Regeneration

Abstract

INTRODUCTION: Diabetes Mellitus (DM) is a systemic disease that affects large part of the population and is considered a relative contraindication to implant therapy. However, there are studies showing that the survival rate of implants in type-2 diabetic patients is approximately 90%, approaching that of non-diabetic patients. It is also shown that these results are strictly correlated with the importance of glycemic control to provide predictability of success rates and improve osseointegration of the implants inserted. There is no evidence whether controlled type-1 diabetes is or is not a risk factor for implant failure. OBJECTIVES: The objective of this study was to clinically and radiographically evaluate the success of implant overdenture in controlled type-1 diabetic patients. MATERIALS AND METHODS: Ten completely edentulous well controlled type-1 and ten non-diabetic patients were selected and divided into group I and II respectively. All patients received three implant assisted mandibular overdentures through minimally invasive flapless technique. Clinical evaluation of implant stability was performed using Osstell ISQ immediately after implant placement (base line), four months and one year after prosthesis insertion. Level of alveolar bone loss around each abutment was also evaluated using Cone Beam Computed Tomography (CBCT) at the time of final prosthesis insertion (base line), four months and one year after insertion. RESULTS: Of the ten patients in the study group, two patients were lost yielding a success rate of 80 % in group I. Clinical results of implant stability test showed significant decrease in stability in the study group as compared to the control group, also radiographical results revealed significant increase in amount of average crestal bone loss in the diabetic patients. CONCLUSIONS: Within the limitations of this study, and based on the clinical level, the implant overdenture may be recognized as being predictable treatment option for controlled type-1 diabetic patients.

PRF and Sticky Bone as Regenerative Materials in Oral Surgery

“…Sticky bone is a mixture of autologous fibrin glue and bone grafts (autografts, xenografts, allografts) [25]. Sticky bone is also known as a mineralized plasmatic matrix [26][27][28][29][30][31][32][33][34][35][36][37][38]. A bone graft obtained in this way is gelatinous in structure, which renders it for shaping.…”