Evaluation of treatment adherence in outpatients with schizophrenia

Chaudhari, Bhushan; Saldanha, Daniel; Kadiani, Adnan; Shahani, Roma

doi:10.4103/ipj.ipj_24_17

Cited by 35 publications

(43 citation statements)

References 29 publications

(45 reference statements)

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“…In the current study, the patient's interview and self‐filled survey lasted approximately 1½ hrs, which might eventually be too long or challenging for patients with SZ and significant cognitive impairments. Given a higher social‐functioning level (Novick et al, ) and moderate illness severity (Chaudhari, Saldanha, Kadiani, & Shahani, ) associated with better medication adherence, it may potentially impact our results in the SZ group. In addition, it is possible that the information related to the treatment of SZ is more consistent.…”

Section: Discussionmentioning

confidence: 98%

Health‐related Internet use and treatment adherence: A transdiagnostic comparison of outpatients with major depressive disorder and schizophrenia

2020

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Treatment adherence is relevant for clinical and economic outcome in affective disorders as well as psychosis. Knowledge concerning the disease and its treatment might influence patients' willingness to follow the health-care providers' recommendations and mutual decision-making. In the current study, we investigated how Internet surfing for health-related issues and attitude toward the relevance of the online information impact treatment adherence in major depressive disorder (MDD) and schizophrenia (SZ). A total of 83 outpatients (59 MDD, 24 SZ) participated in a survey. A multiple linear regression model with "exposure," "attitude," "diagnosis," and their interaction as regressors was significant predictive of medication-adherence rating scores, R 2 = .179; 95% CI [0.00, 0.32]. In the MDD group only, more extended exposure to Internet surfing for health-related issues and attribution of higher personal relevance were associated with poorer medication adherence at a statistical trend level, p = .060 and p = .077, respectively. In both groups, being female as well as higher age and intelligence were associated with favorable adherence, p = .003, p = .044, and p = .039, respectively. Considering the limitations (e.g., small sample size), our findings add to previously published data contributing to a better understanding of how Internet use may impact treatment adherence in MDD and schizophrenia.

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Section: Discussionmentioning

confidence: 98%

Health‐related Internet use and treatment adherence: A transdiagnostic comparison of outpatients with major depressive disorder and schizophrenia

2020

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“…The mean score on positive, negative and general psychopathology domain assessed by PANSS were significantly correlated with non-adherence in our study and was accordance to various previous studies. [23][24][25][26] The reason for increase in PANSS scale score being associated with non-compliance could be paranoia or uncooperativeness, loss of volition and in particular low recognition of the need for treatment. The mean insight score on G12 domain of PANSS was significantly higher (5.37 ) in patients who were non-adherent to medication in comparison to adherent group (P< 0.001).…”

Section: Discussionmentioning

confidence: 99%

Severity Of Relapse And Medication Adherence In Patient Of Schizophrenia: A Study From Nepal

Singh

Karmacharya

Khadka

2019

J Psychiatr Assoc Nepal

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Introduction: Schizophrenia is a clinical syndrome of variable, but profoundly disruptive psychopathology. Though it is one of the top ten illness contributing to global burden of disease, relapse rate in schizophrenia is high. Globally relapse rate varies from 50% to 92% and are similar in developed and developing countries. There are various factors associated with relapse, common being poor adherence to treatment. The estimated rate of non-adherence in schizophrenia are 50% widely ranging from 4% to 72%. This study was aimed to find the socio-demographic status of non-adherent group, contributing factors and their severity. Material and Method: A descriptive, cross-sectional study among 95 schizophrenia relapsed patients seeking psychiatric inpatient services at Nepal Medical College Teaching Hospital, Attarkhel, Nepal from the period of Baisakh 3rd 2074 to Baisakh 4th 2075. The socio-demographic variables and clinical data of patients were recorded on proforma developed by department of Psychiatry. The severity of illness was assessed by using The Brief Psychiatric Rating Scale (BPRS) and Positive And Negative Syndrome Scale (PANSS). Also, medication adherence was assessed using Medication Adherence Rating Scale (MARS). Results: Out of 95 relapsed patients, greater number (62.1%) were non-adherent to medication and (37.9%) were adherent to medication. Also, the symptom severity assessment showed significantly severe relapse in non-adherent patient group (43.1%) than adherent patient group (3.1%). Conclusion: Non-adherent to medication is associated with significantly severe relapse in patients of Schizophrenia. Therefore, improving adherence to medication can be achieved by focusing on the identified multitude of factors driving non-adherence.

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“…A study observed a rate of 52% for nonadherence to treatment in schizophrenia patients in India. [ 28 ] To address the problems of nonadherence, the family practiced surreptitious medication/covert medication. [ 29 ]…”

Section: Relevance Of Community Treatment Order In Indian Mental Healmentioning

confidence: 99%

Is it the right time to implement Community Treatment Order in India?

Gowda

Enara

Raveesh

et al. 2019

Indian J Psychiatry

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Evaluation of treatment adherence in outpatients with schizophrenia

Cited by 35 publications

References 29 publications

Health‐related Internet use and treatment adherence: A transdiagnostic comparison of outpatients with major depressive disorder and schizophrenia

Health‐related Internet use and treatment adherence: A transdiagnostic comparison of outpatients with major depressive disorder and schizophrenia

Severity Of Relapse And Medication Adherence In Patient Of Schizophrenia: A Study From Nepal

Is it the right time to implement Community Treatment Order in India?

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