Evaluation of trace metals in thyroid tissues: Comparative analysis with benign and malignant thyroid diseases

Stojsavljević, Aleksandar; Rovčanin, Branislav; Krstić, Đurđa; Borković-Mitić, Slavica; Paunović, Ivan; Kodranov, Igor; Gavrović-Jankulović, Marija; Manojlović, Dragan

doi:10.1016/j.ecoenv.2019.109479

Cited by 33 publications

(20 citation statements)

References 36 publications

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“…As shown in Table 3 , the average recoveries of metals in spice samples were ranged from 92.62% to 107.13%, indicating that the method was accurate and applicable for the determination of metals in spice samples [ 23 , 24 ].…”

Section: Resultsmentioning

confidence: 99%

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Health risk assessment of heavy metals in selected Ethiopian spices

Tefera

Teklewold

2021

Heliyon

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A total of 144 spice samples (ajwain, black cumin, coriander and fenugreek) were collected from three districts. For the determination of heavy metals (Cd, Cr, Cu, Pb and Zn) concentrations and human health risks, the spice samples were digested in a mixture of HNO 3 and HClO 4 . The highest concentrations of Cr (24.85 AE 1.673 mg/kg) and Cu (32.267 AE 7.355 mg/kg) were investigated in ajwain and Zn (54.13 AE 6.122 mg/kg) in fenugreek. However, lowest concentration of Cr and Cu were detected in fenugreek; and Zn in coriander. Cd and Pb were not detected in all spice samples. A positive correlation was observed among Cr, Cu and Zn in fenugreek; Zn with Cr and Cu in black cumin and Zn with Cu in ajwain and coriander. However, negative correlation was observed Cr with Cu and Zn in ajwain and coriander; Cr with Cu in black cumin. THQ values of Cu, Zn and 75% of Cr in all spices were less than 1. About 66.7% of the HI values of the samples under study were less than 1, indicated that the consumers will not experience potential health risks from the intake of individual metals through spices consumption.

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Section: Resultsmentioning

confidence: 99%

“…It has no beneficial role in human metabolism and produces a progressive toxicity even at lower levels and there is no known safe exposure level. It is accumulated in humans and animals mainly in the liver and kidneys [ 24 , 31 , 32 ].…”

Section: Resultsmentioning

confidence: 99%

Health risk assessment of heavy metals in selected Ethiopian spices

Tefera

Teklewold

2021

Heliyon

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“…These studies also tend to track and follow-up health policies that refer to the monitoring of exposure to toxic trace elements, as well as their quantification during diagnostic and detoxification treatments (Kim et al 2014 ; Cui et al 2017 ). Since human exposure originates from natural and anthropogenic sources, it is necessary to take into account cumulative effects that can only be assessed by solid tissue analysis, and to evaluate the potential health consequences for the examined population (Stojsavljević et al 2019 ). Although whole blood and serum samples are widely used in HBM studies, more detailed information about the intrinsic conditions in the human body can be obtained by analysing solid tissue samples.…”

Section: Introductionmentioning

confidence: 99%

Possible zinc deficiency in the Serbian population: examination of body fluids, whole blood and solid tissues

Jagodić

Rovčanin

Borković-Mitić

et al. 2021

Environ Sci Pollut Res

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“…This makes thyroid tissue very useful in public health studies. However, thyroid tissue samples are only available after surgery, biopsy or autopsy (Stojsavljević et al 2019b), which likely explains the small number of HBM studies performed on thyroid tissues.…”

Section: Healthy Thyroid Tissue and Essential Trace Metalsmentioning

confidence: 99%

Impact of Essential and Toxic Trace Metals on Thyroid Health and Cancer: A Review

Stojsavljević

Rovčanin

2021

Expo Health

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Most investigations conducted in the last four decades have shown a rising incidence of thyroid diseases worldwide. Although our knowledge of the molecular pathways of thyroid disease has advanced, the initial steps in thyroid cancerogenesis have not yet been sufficiently elucidated. However, recent human biomonitoring studies have shown that specific trace metals, as major endocrine disrupters, could be considered as risk factors for impaired thyroid health and the evolution of thyroid cancer (TC). In this review, the impact of essential and toxic trace metals from the environment on thyroid health and TC was evaluated. Furthermore, this review clarifies which trace metals most likely contribute to the etiology of TC. Biomarkers based on trace metal ratios are proposed. Overall, the information described in this review is expected to be useful in planning future fundamental and applied studies on the endocrine toxicity of essential and toxic trace metals.

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Evaluation of trace metals in thyroid tissues: Comparative analysis with benign and malignant thyroid diseases

Cited by 33 publications

References 36 publications

Health risk assessment of heavy metals in selected Ethiopian spices

Health risk assessment of heavy metals in selected Ethiopian spices

Possible zinc deficiency in the Serbian population: examination of body fluids, whole blood and solid tissues

Impact of Essential and Toxic Trace Metals on Thyroid Health and Cancer: A Review

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