Evaluation of tissue response to MTA and Portland cement with iodoform

Morais, Carlos Alberto Herrero de; Bernardineli, Norberti; Garcia, Roberto Brandão; Duarte, Marco Antônio Húngaro; Guerisoli, Danilo Mathias Zanello

doi:10.1016/j.tripleo.2005.09.028

Cited by 47 publications

(55 citation statements)

References 20 publications

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“…Húngaro-Duarte et al (11), Coomaraswamy et al (27) and de Morais et al (30) showed that addition of bismuth oxide to PC dramatically changed the material constants; these results have stimulated the search for an alternative radiopacifying agent for use with PC. Addition of other radiopacifying agents such as zirconium oxide and iodoform results in a cement with greater radiopacity than dentin, and both of these agents are present in the formulations of several other endodontic sealants.…”

Section: Discussionmentioning

confidence: 99%

“…The iodoform was tested as a radiopacifier for addition to Portland cement because of its satisfactory radiopacity, its widespread availability to clinicians, and earlier reports indicating that it is harmless to pulp and periapical tissues (28,30). The zirconium oxide, a bioinert material with good biocompatibility, has been confirmed to have good biocompatibility and no cytotoxic effects on fibroblasts (20,31).…”

Section: Discussionmentioning

confidence: 99%

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Biocompatibility of Portland cement combined with different radiopacifying agents

et al. 2014

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The aim of this study was to evaluate the response of rat subcutaneous tissue to Portland cement combined with two different radiopacifying agents, iodoform (CHI 3 ) and zirconium oxide (ZrO 2 ). These materials were placed in polyethylene tubes and implanted into the dorsal connective tissue of Wistar rats for 7 and 15 days. The specimens were then stained with hematoxylin and eosin, and inflammatory reaction parameters were evaluated by light microscopy. The intensity of the inflammatory response to the sealants was analyzed by two blind calibrated observers throughout the experimental period. Histological analysis showed that all the materials caused a moderated inflammatory reaction at 7 days, which then diminished with time. At 15 days, the inflammatory reaction was almost absent, and fibroblasts and collagen fibers were observed indicating normal tissue healing. The degrees of the inflammatory reaction on different days throughout the experimental period were compared using the non-parametric Kruskal-Wallis test. Statistical analysis demonstrated no significant differences amongst the groups, and Portland cement associated with radiopacifying agents gave satisfactory results. Therefore, Portland cement used in combination with radiopacifying agents can be considered a biocompatible material. Although our results are very encouraging, further studies are needed in order to establish safe clinical indications for Portland cement combined with radiopacifying agents. (J Oral Sci 56, 29-34, 2014)

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Biocompatibility of Portland cement combined with different radiopacifying agents

et al. 2014

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“…[1][2][3][4][5] Possui uma ampla variedade de aplicações clínicas, destacando -se o selamento de perfurações e o preenchimento de cavidades retrógradas em cirurgias parendodônticas 1,3 devido à sua capacidade seladora, 1 e por estimular a deposição de tecido mineralizado reparador. [6][7][8] O MTA atualmente apresenta duas versões comerciais distintas, sendo uma de cor cinza e outra de cor branca.…”

Section: Introductionunclassified

Solubilidade e desintegracao de cimentos a base de agregados minerais contendo diferentes radiopacificadores

Silva¹,

García²,

Henriques³

et al. 2017

j.rpemd

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“…Diversas alternativas podem ser propostas com o intuito de proporcionar radiopacidade ao cimento Portland, como iodofórmio 12,13 , sulfato de bário 14 , carbonato de bismuto e, também, o próprio óxido de bismuto em diferentes proporções 15,16 . A opção pelo óxido de bismuto ocorre em função de seu alto peso molecular 13 .…”

Section: Introductionunclassified

Análise físico-química do MTA e do cimento Portland associado a quatro diferentes radiopacificadores

Costa

Campos

Duarte

et al. 2014

Rev. odontol. UNESP

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ResumoIntrodução: O Mineral Trióxido Agregado (MTA) é composto por cimento Portland (CP) e um radiopacificador (óxido de bismuto). Objetivo: Avaliar tempo de presa, solubilidade, pH, liberação de íons Cálcio e radiopacidade do cimento Portland puro ou associado a quatro radiopacificadores (sulfato de bário, carbonato de bismuto, óxido de bismuto e iodofórmio), comparados ao MTA branco (Angelus, Londrina, Brasil). Material e método: A proporção empregada CP/radiopacificador foi de 4:1 em peso, (80% de cimento Portland e 20% de radiopacificador Descritores: Mineral trióxido agregado; obturação retrógrada; materiais retrobturadores. AbstractIntroduction: Mineral Trioxide Aggregate (MTA) is composed of Portland cement (PC), and a radiopacifier (bismuth oxide). Objective: To evaluate the setting time, solubility, pH, calcium ion release and radiopacity of pure Portland cement and its association to four radiopacifiers, (Barium sulfate, bismuth carbonate, bismuth oxide and iodoform), and White MTA (Angelus, Londrina, Brazil). Material and method: The ratio CP/radiopacifier used was 4:1 by weight (80% Portland cement and 20% radiopacifier). The setting time was evaluated according the specification ADA 57. The solubility was analyzed according to ISO 6876/2001 specification. The pH was evaluated using a digital pHmeter and the release of Ca ++ ions by atomic absorption spectrophotometer. The radiopacity was measured in millimeters of aluminum (mm/Al). The results were submitted to ANOVA and Tukey tests using 5% of significance level. Result: Barium sulfate did not alter the final setting time of the PC. Observed radiopacity was less than the minimum recommended by ADA 57 and ISO 6876/2001 for CP and CP associated with barium sulfate. The PC associated with iodoform showed solubility above the 3% recommended by ISO 6876/2001. All materials provided alkalinization and promoted calcium ion release. Conclusion: Bismuth carbonate and bismuth oxide provided proper initial setting time, solubility, pH, calcium ion release and radiopacity when combined with CP.

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Evaluation of tissue response to MTA and Portland cement with iodoform

Cited by 47 publications

References 20 publications

Biocompatibility of Portland cement combined with different radiopacifying agents

Biocompatibility of Portland cement combined with different radiopacifying agents

Solubilidade e desintegracao de cimentos a base de agregados minerais contendo diferentes radiopacificadores

Análise físico-química do MTA e do cimento Portland associado a quatro diferentes radiopacificadores

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