Evaluation of Three Brief Screening Tests for Older Patients with Mild HIVAssociated Neurocognitive Disorders in the cART Era

Introduction: The number of human immunodeficiency virus-associated neurocognitive disorders has increased, reaching more than 50% of the cases. However, there are currently no substantial data on the screening methods for this disease. This study aimed to evaluate and compare the Mini-Mental State Examination to the Montreal Cognitive Assessment in human immunodeficiency virus-infected patients. Methods: This was an observational study comprising 82 human immunodeficiency virus-positive individuals with and without cognitive complaints. Results: Positive correlation (p<0.001) between the Mini-Mental State Examination and the Montreal Cognitive Assessment test scores was observed, but the mean scores revealed that the Mini-Mental State Examination showed worse performance for trails (p<0.001), cube copying (p<0.001), and clock drawing (p<0.001) than the Montreal Cognitive Assessment. Conclusions: The Mini-Mental State Examination and the Montreal Cognitive Assessment tests should be used concomitantly for the assessment of human immunodeficiency virus-associated neurocognitive disorders, but visuoexecutive and visuospatial dysfunctions are better evaluated using the Montreal Cognitive Assessment test than the Mini-Mental State Examination.

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Evaluation of Three Brief Screening Tests for Older Patients with Mild HIVAssociated Neurocognitive Disorders in the cART Era

Abstract: Introduction: Prevalence of HIV-associated neurocognitive disorders (HAND) in the era of antiretrovirals is still high, the majority of clinical phenotypes being represented by mild forms of impairment. Therefore, adequate screening strategies are needed.

Cited by 2 publications

References 31 publications

Validation of a rapid and easy-to-perform screening test for neurocognitive impairment in HIV+ patients

Validation of a rapid and easy-to-perform screening test for neurocognitive impairment in HIV+ patients

Comparison between the Mini-Mental State Examination and Montreal Cognitive Assessment as a Cognitive Screening Tool in Patients with Human Immunodeficiency Virus-Associated Neurocognitive Disorders

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