Validation of a rapid and easy-to-perform screening test for neurocognitive impairment in HIV+ patients

Joly, H.; Vassallo, Mattéo; Issaurat, Margaux; Fabre, Roxane; Pradier, Christian; Lebrun-Frénay, Christine

doi:10.1016/j.jns.2019.116664

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…Similarly, another CNAD, the Computerized Speed Cognitive Test (CSCT), is also designed to measure information processing speed. This brief test takes about 90 s to complete, during which participants match stimuli presented at the bottom of the screen to a key of symbols presented at the top of the screen [61]. It is available on computer and touchscreen platforms.…”

Section: Computerized Speed Cognitive Test (Csct)mentioning

confidence: 99%

“…One study in Nice and Cannes, France (non-HAND, n = 19; HAND, n = 67; 98% had HIV-RNA below < 50 copies/mL at inclusion), showed a significant difference between groups based on a CSCT z-score with a cutoff of 47 correct responses (mean (SD) = − 0.1 (1.0) vs. − 1.1 (1.6); p < 0.005). Sensitivity and specificity of CSCT based on this cutoff were 81% and 53%, respectively, where HAND was classified from the traditional NP testing as at least two cognitive domains that were 1 SD below the mean [61].…”

Section: Computerized Speed Cognitive Test (Csct)mentioning

confidence: 99%

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Validity of Digital Assessments in Screening for HIV-Related Cognitive Impairment: a Review

et al. 2021

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Purpose of Review While traditional neuropsychological tests are the gold standard in screening for HIV-related cognitive impairment, computerized neuropsychological assessment devices (CNADs) offer an alternative to these time-and resource-intensive batteries and may prove to be particularly useful for remote assessments or longitudinal monitoring. This review seeks to describe the benefits, limitations, and validity of CNADs in the evaluation of HIV-associated neurocognitive disorder (HAND). Recent Findings We identified eight CNADs that have undergone validity testing for cognitive impairment in the setting of HIV. Included among these are batteries that have been modeled after the traditional neuropsychological exam, as well as others that implement new technologies, such as simulated reality and daily ecological assessments in their testing. Summary Currently, these digital batteries do not yet have the ability to supplant gold standard neuropsychological tests in screening for HAND. However, many have the potential to become effective clinical screening tools.

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Section: Computerized Speed Cognitive Test (Csct)mentioning

confidence: 99%

Section: Computerized Speed Cognitive Test (Csct)mentioning

confidence: 99%