Evaluation of the WHO clinical decision rule for streptococcal pharyngitis

Rimoin, Anne W.; Hamza, Hala; Vince, Adriana; Kumar, Rahul; Walker, Christa L. Fischer; Chitale, Rohit A.; Cunha, Antonia L. A. da; Qazi, Shamim; Steinhoff, Mark C.

doi:10.1136/adc.2004.069120

Cited by 56 publications

(57 citation statements)

References 15 publications

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“…We reviewed 30 full-text articles, of which 11 were included (Supplemental Fig 7). [46][47][48][49][50][51][52][53][54][55][56] Previous antimicrobial exposure was not mentioned in 4 studies but was assumed to be absent owing to the studies' prospective nature 51,53 and subjects' acute presentation. 55,56 Mean age was available in 6 (55%) studies and averaged 75.6 months (Supplemental Appendix 2).…”

Section: Pharyngitismentioning

confidence: 99%

Bacterial Prevalence and Antimicrobial Prescribing Trends for Acute Respiratory Tract Infections

Kronman¹,

2014

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WHAT'S KNOWN ON THIS SUBJECT: Many pediatric acute respiratory tract infections (ARTI) are viral and do not require antimicrobial treatment. Recent estimates of antimicrobial overprescribing for these infections, defined based on the published bacterial disease prevalence among all ARTI, are not available. WHAT THIS STUDY ADDS:Based on the published bacterial prevalence rates for pediatric ARTI, antimicrobial agents are prescribed almost twice as often as expected to outpatients nationally, amounting to an estimated 11.4 million potentially preventable antimicrobial prescriptions annually. abstract BACKGROUND AND OBJECTIVES: Antimicrobials are frequently prescribed for acute respiratory tract infections (ARTI), although many are viral. We aimed to determine bacterial prevalence rates for 5 common childhood ARTI -acute otitis media (AOM), sinusitis, bronchitis, upper respiratory tract infection, and pharyngitis-and to compare these rates to nationally representative antimicrobial prescription rates for these ARTI. METHODS:We performed (1) a meta-analysis of English language pediatric studies published between 2000 and 2011 in Medline, Embase, and the Cochrane library to determine ARTI bacterial prevalence rates; and (2) a retrospective cohort analysis of children age ,18 years evaluated in ambulatory clinics sampled by the 2000-2010 National Ambulatory Medical Care Survey (NAMCS) to determine estimated US ARTI antimicrobial prescribing rates. RESULTS:From the meta-analysis, the AOM bacterial prevalence was 64.7% (95% confidence interval [CI], 50.5%-77.7%); Streptococcus pyogenes prevalence during pharyngitis was 20.2% (95% CI, 15.9%-25.2%). No URI or bronchitis studies met inclusion criteria, and 1 sinusitis study met inclusion criteria, identifying bacteria in 78% of subjects. Based on these condition-specific bacterial prevalence rates, the expected antimicrobial rescribing rate for ARTI overall was 27.4% (95% CI, 26.5%-28.3%). However, antimicrobial agents were prescribed in NAMCS during 56.9% (95% CI, 50.8%-63.1%) of ARTI encounters, representing an estimated 11.4 million potentially preventable antimicrobial prescriptions annually.

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Section: Pharyngitismentioning

confidence: 99%

Bacterial Prevalence and Antimicrobial Prescribing Trends for Acute Respiratory Tract Infections

Kronman¹,

2014

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“…Based on cost, narrow spectrum of activity, safety, and effectiveness, penicillin is recommended by the American Academy of Family Physicians (AAFP) [18], the American Academy of Pediatrics (AAP) [19], the American Heart Association (AHA) [20], the Infectious Diseases Society of America (IDSA) [21], and WHO for the treatment of streptococcal pharyngitis [22]. Penicillin is often substituted by amoxicillin oral suspension due to its better taste.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Rational Drug Use for Acute Pharyngitis Associated with the Incidence and Prevalence of the Disease at Two Community Health Centers in Indonesia

Yuniar

Anggadiredja

Islamiyah

2016

Preprint

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Abstract:According to Indonesia's Result of Basic Health Research of 2013, prevalence of acute respiratory infection in 2007 and 2013 were not significantly different (25.5% and 25.0%, respectively). Identifying the cause of acute pharyngitis is a key point in determining the optimal treatment. The main purpose is to evaluate the rational use of drugs and its irrational impact as well as the correlation of the drug use with the incidence and prevalence of acute pharyngitis. This study was a descriptive and observational study, carried out retrospectively and concurrently at two community health centers located in Bandung and Cimahi, Indonesia. There was overprescription of antibiotics in 80.01% of prescription cases, with a total of 8.98% being non-treatment option, and 62.43% being irrational use of corticosteroids. The incidence and prevalence of acute pharyngitis at one health center in Bandung were 2.45% and 2.31%, respectively, with an irrationality rate of 83.82%. Those recorded at one health center in Cimahi were 2.11% incidence and 2.00% prevalence with an irrational rate of 91.29%. It can be concluded that there is still an irrational use of medicines in the treatment of acute pharyngitis in community health centers. The higher incidence and prevalence might indicate the declining quality of health services.

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“…БГСА фарингит и тонзиллит обычно развиваются у детей школьного воз-раста (до 37%); у детей до 5 лет его частота ниже (до 24%), что подтверждает необходимость проведения экспресс-диагностики и культуральных исследований в этих воз-растных группах больных [44]. Распространенность острой БГСА-инфекции верхних дыхательных путей у детей до 3 лет оценивается в 10-14%, а по некоторым данным, не превышает 6% [45,46]. Кроме того, развитие острой ревматической лихорадки не свойственно детям в этом возрасте [47].…”

Section: кому проводить экспресс-тест и культуральное исследование наunclassified

Diagnosis of Acute Pharyngitis in Children

et al. 2014

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Evaluation of the WHO clinical decision rule for streptococcal pharyngitis

Cited by 56 publications

References 15 publications

Bacterial Prevalence and Antimicrobial Prescribing Trends for Acute Respiratory Tract Infections

Bacterial Prevalence and Antimicrobial Prescribing Trends for Acute Respiratory Tract Infections

Evaluation of Rational Drug Use for Acute Pharyngitis Associated with the Incidence and Prevalence of the Disease at Two Community Health Centers in Indonesia

Diagnosis of Acute Pharyngitis in Children

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