“…Some of the PICCs benefits are: the ability to maintain prolonged therapy with fewer vein punctures, the low incidence of infection, the possibility to insert this device at bedside, the possibility to administer parenteral nutrition with dextrose concentration greater than 10%, vesicant, irritant, vasoactive drug and solutions with extreme osmolarity or non physiological pH. 1 - 3 , 4 , 5 - 7 PICC began to be used in Brazil in the early 1990s, initially in neonatal patients. 5 Its use quickly expanded to patients of all ages due to its advantages over other central venous catheters, including reduced risk of pneumothorax and sepsis resulting from colonization of the skin around the insertion point, lower insertion costs compared with other central venous catheters, easy maintenance, and the ability to discharge patients while still continuing antibiotic therapy and chemotherapy.…”