Evaluation of the soothing effect of Eupilen® topical formulation on radiotherapy-induced dermatitis

MASCC clinical practice guidelines for the prevention and management of acute radiation dermatitis: part 1) systematic review

“…Insufficient evidence was reported to support the use of urea, Xonrid, hydroactive colloid gel, and other interventions. 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 Topical corticosteroids 18 (15) 1715 (81; 12–219) Mometasone furoate (8); Betamethasone (6); Other (4) Breast (14); Head and neck (3); Multiple (1) Mometasone furoate and betamethasone were both generally found to be effective in ARD prevention. There is insufficient evidence supporting the use of other corticosteroids, such as hydrocortisone and beclomethasone.…”

“…A total of 42 studies assessed topical non-steroidal agents for the prevention of ARD, including 12 and 28 non-randomized studies and RCTs, respectively 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 ( Appendix C, Table 1 ). The majority of RCTs assessed trolamine-based products (including Biafine ®), 14 , 15 , 16 , 17 , 18 , 21 , 33 hyaluronic acid/hyaluronan-based products, 22 , 23 , 24 , 25 , 26 and heparinoid (Hirudoid ®).…”

Prospective Efficacy and Safety Study of an Innovative Kerascalp Hair Growth Serum in Mild-to-Moderate Alopecia in India: Regrowth Study

“…At the end of the three-month treatment, in the test group, there were significant improvements in trichogram findings - a significant increase of hair in anagen phase and a significant decrease of hair in telogen and dystrophic anagen phases have been observed. Moreover, the subjective evaluation of the efficacy and the cosmetic parameters of the tested lotion showed an overall positive effect [ 16 ].…”

“…Ximenynic acid, a di-unsaturated fatty acid, is found in many plant species such as Ximenia africana (wild plum) and Santalum album (Indian sandalwood). Ximenynic acid is considered a precursor or stimulator of the biosynthesis of eicosanoids which endows the microvascular kinetic activity at the level of small arteries [ 16 ]. Lauric acid, saturated fatty acid extracted from natural substances, has a high affinity for hair proteins, and because of its low molecular weight and a straight linear chain structure, it is able to penetrate inside the hair shaft, thereby exerting a protective effect on the damaged hair.…”

“…Lauric acid, saturated fatty acid extracted from natural substances, has a high affinity for hair proteins, and because of its low molecular weight and a straight linear chain structure, it is able to penetrate inside the hair shaft, thereby exerting a protective effect on the damaged hair. In vitro studies have also demonstrated the inhibitory action of lauric acid on 5-α-reductase thus reducing the activity of DHT, addressing the principal pathophysiology of AGA [16][17][18].…”