Evaluation of the RYR1 gene genetic diversity in the Latvian White pig breed

Dokane, Kristine; Jonkus, D.; Sjakste, Tatjana

doi:10.7124/bc.00091d

Cited by 1 publication

(2 citation statements)

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“…Thus the, unfavourable allele is not present in Latvian White pigs. The rs323041392 in the Latvian White pig has lost variability on the farms over the past nine years (Dokāne et al, 2016). At the same time, these researchers emphasize that the Latvian and European livestock industries need to keep in mind that intensification of reproduction can reduce genetic diversity, specific performance characteristics and adaptability to environmental problems in local breeds in small populations (Dokāne et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

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DNA-type results of Landrace sows for RYR1-gene and its association with productivity

Tsereniuk

Bobrytska

Miroshnikova

et al. 2020

Regul. Mech. Biosyst.

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Recently the assessment of QTL genes has been a relevant focus of research. Among other genes, the RYR1 is one of the most important. Research on this gene for Landrace sows of Ukrainian selection has been insufficient. This fact confirms the need for our work. A total of 63 Landrace sows from different families were evaluated by reproductive qualities for two generations. A comprehensive assessment of the sows’ reproductive ability was performed using the SIRQS-index. Determination of polymorphism in the RYR1 gene in pigs was performed by using DNA-typing of animals. Genetic potential was calculated between two generations “mother-daughter”. By assessment of polymorphism of the RYR1 gene, it was found that 6.3% of the Landrace sows were the carriers for the mutant allele of the RYR1 gene. No animals with the RYR1nn genotype were detected. Accordingly, animals with the RYR1NN genotype accounted for 93.6%. The frequency of the N allele of the RYR1 gene was 0.97, the n frequency of the RYR1 gene allele was 0.03. Sows with RYR1NN genotype had a higher level of reproductive ability compared to the RYR1Nn genotype. RYR1NN genotype also had a higher level of genetic potential. The greatest progress was established between generations of Landrace sows which were carriers for the mutant allele. The highest values of this progress were by the NBA, the lowest – by the NW. On the contrary, there was regression between populations for part of the population (Landrace sows of Ukrainian selection of RYR1Nn genotype) by the all estimated indicators of reproductive ability. Sows that were free of the mutant allele of the RYR-1 gene had high SIRQS index. The phenotypic consolidation coefficients by the NBA were lower for sows free of the mutant allele than for its carrier. The advantage of sows free of the mutant allele of the RYR-1 gene over its carrier sows was established in almost all assessed indicators of reproductive ability. No significant differences in the level of consolidation of reproductive ability between sows with different allelic variants of the RYR-1 gene were established. The higher productive level of sows with RYR1NN genotype is reflected in the indicators of economic efficiency of production. It allows higher levels of profitability to be obtained and net profit to be increased by 1093 UAH compared to sows with RYR1Nn genotype. The further monitoring of the studied gene and the gradual elimination of carriers of the mutant allele is a promising direction in breeding work.

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Section: Discussionmentioning

confidence: 99%

“…Some of them were associated with specific phenotypes. However, data on the genetic variability of RYR1 in pigs are scarce (Dokāne et al, 2016). An important point of the assessment of the RYR1 gene is also the fact that this gene is largely reflected in product quality, particularly in marketable pork.…”

Section: Introductionmentioning

confidence: 99%