2015
DOI: 10.1016/j.dld.2015.03.011
|View full text |Cite
|
Sign up to set email alerts
|

Evaluation of the red cell distribution width as a biomarker of early mortality in hepatocellular carcinoma

Abstract: The red cell distribution width is a novel, reproducible, prospectively validated predictor of survival in patients with hepatocellular carcinoma.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

2
46
0

Year Published

2016
2016
2021
2021

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 34 publications
(48 citation statements)
references
References 42 publications
2
46
0
Order By: Relevance
“…Previous studies showed that the RDW increased in patients with malignant tumors, [911,1518] which is consistent with the findings of the present study. Ay et al [15] compared the RDW in patients with benign and malignant tumors of the colon, including 115 patients with colon polyps and 30 with colon cancer.…”
Section: Discussionsupporting
confidence: 93%
See 1 more Smart Citation
“…Previous studies showed that the RDW increased in patients with malignant tumors, [911,1518] which is consistent with the findings of the present study. Ay et al [15] compared the RDW in patients with benign and malignant tumors of the colon, including 115 patients with colon polyps and 30 with colon cancer.…”
Section: Discussionsupporting
confidence: 93%
“…Related research has mainly focused on endometrial cancer, lung cancer, and liver cancer. [911] To the best of our knowledge, however, the relationship between the RDW and ovarian cancer has not yet been described. In the present study, we analyzed the correlation between the RDW and ovarian cancer by observing changes in the RDW in patients with ovarian cancer.…”
Section: Introductionmentioning
confidence: 99%
“…After removed duplicate and irrelevant papers, a total of 16 articles were included in this analysis. For case ascertainment, fifteen articles [1327] performed retrospective analysis (3953 participants), and one article [28] had both a retrospective design and a prospectively design in two independent patients population (314 participants). Therefore, a total of 16 articles including 17 studies with 4267 patients were included in this analysis with a median sample size of 179 (from 81 to 938).…”
Section: Resultsmentioning
confidence: 99%
“…RDW reflects inflammation-induced erythroid maturation impairment and has clinical utility as a marker of inflammation in both liver disease [15, 16, 17] and cancer [18]. Inflammation is central to liver damage, fibrogenesis and oncogenesis [10, 19], and inflammatory markers have prognostic value in HCC [20, 21].…”
Section: Discussionmentioning
confidence: 99%
“…Several groups have previously shown that inflammatory parameters, including the Inflammation-based Index (IBI) and the neutrophil to lymphocyte ratio (NLR), are associated with worse survival in HCC [11–14]. More recently, we demonstrated that stage-dependent deterioration in red cell distribution width (RDW), a marker of anistocytosis, is associated with overall survival in HCC, with the strongest prognostic role of RDW demonstrated in patients with advanced HCC [15]. Moreover, inflammatory parameters such as RDW are inexpensive and accessible biomarkers for survival prediction in HCC.…”
Section: Introductionmentioning
confidence: 99%