“…The initial substance used, 1311-labelled " diodrast," is concentrated in the liver and has been superseded by other substances, the most satisfactory being 1311-labelled " hippuran," sodium salt of orthoiodohippuric acid (Nordyke et al, 1960). Published reports on the detection of unilateral renal disease using radioactive diodrast or diatrizoate have been both favourable (Winter et al, 1959;Serratto et al, 1959;Denneberg and Hedenskog, 1959;Block et al, 1960;Straffon and Garcia, 1960) and unfavourable (Poker et al, 1960;Saterborg, 1960;Dollery, 1960;Moses et al, 1961). In this paper we report the results of 1311-hippuran renography in 203 hypertensive patients and assess the value of the test when used in conjunction with the intravenous pyelogram to select individuals for aortography and divided renal-function tests.…”