131I-"Hippuran" Renography in Detection of Unilateral Renal Disease in Patients with Hypertension

Doig, A.; Lawrence, J. R.; Philip, T.; Tothill, P.; Donald, K. W.

doi:10.1136/bmj.1.5329.500

Cited by 27 publications

(6 citation statements)

References 17 publications

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“…28 We feel that the reno¬ gram, while of importance in the detection of renal disease,29·30 offers little aid to dif¬ ferential diagnosis.31 The fact that the reno¬ gram is not useful in making etiological diagnoses32 is of no consequence in this context, but a number of false-negatives were seen in the present series associated with curable renovascular disease. 28 We feel that the reno¬ gram, while of importance in the detection of renal disease,29·30 offers little aid to dif¬ ferential diagnosis.31 The fact that the reno¬ gram is not useful in making etiological diagnoses32 is of no consequence in this context, but a number of false-negatives were seen in the present series associated with curable renovascular disease.…”

Section: Commentmentioning

confidence: 80%

Renovascular Hypertension

Hocken¹

1966

Arch Intern Med

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Section: Commentmentioning

confidence: 80%

Renovascular Hypertension

Hocken¹

1966

Arch Intern Med

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“…But the results with this method are often difficult to interpret, and though some workers have been enthusiastic" 1 many have been disappointed. '7 18 It is useful as a screening test since there is little discomfort to the patient. Scintillation scanning of the kidney to show concentration in the tubules of 2 3Hg-chloromerodrin after this has been given by intravenous injection is claimed to give sharper definition than the "1I-hippuran renogram, since its accumulation in the kidney depends on renal blood flow and tubular efficiency.…”

Section: Problem Of Renal Hypertensionmentioning

confidence: 99%

Problem of Renal Hypertension

1965

BMJ

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“…At dmes, there may be a difference between the right and the left renogram without any demonstrable cause. Similarly, there may be a unilateral arterial stenosis without differences in the two renograms (1,2,4,9,12).…”

Section: Le Rénogramme Isotopique: éTude De La Reproductibilité Et Inmentioning

confidence: 99%

Isotope Renography with Special Reference to Reproducibility and Significance of Patient Position

Friis¹,

Krogsgaard²

1968

Nephron

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The reproducibility of the three parameters used in isotope renography (T/2 = time from the maximum until half the radioactivity over the kidney had been attained; t = time from injection until the maximum value was attained; and the maximum value) was studied in 41 patients by repeat tests in the same position. The influence of patient position to the same three parameters was also studied in 61 patients investigated in sitting and prone position. The values could be reproduced in 70–98% of the patients in the same position with a fairly wide definition of the concept reproducibility. Patient position was of no significance to the reproducibility. When changing from the sitting to the prone position, the maximum value decreased, while T/2 and t did not show any systematic alteration. A disparity between the function of the two kidneys was demonstrated with the same frequency in the sitting and prone position. This disparity between the two sides was more easily reproducible when X-ray examinations revealed unilateral renal disease. It is concluded that the reproducibility in isotope renography is not fully satisfactory. In the event of a disparity between the two sides the test should be repeated, and if there is a clinical or radiological suspicion of unilateral renal disease, one normal isotope renography should not be relied on, but the test repeated.

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131I-"Hippuran" Renography in Detection of Unilateral Renal Disease in Patients with Hypertension

Cited by 27 publications

References 17 publications

Renovascular Hypertension

Renovascular Hypertension

Problem of Renal Hypertension

Isotope Renography with Special Reference to Reproducibility and Significance of Patient Position

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