Evaluation of the Prediabetic State During Pregnancy

Carrington, Elsie R.; Shuman, Charles R.; Reardon, Helen S.

doi:10.1097/00006250-195706000-00008

Cited by 75 publications

(25 citation statements)

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“…As early as in the 1940s, it was recognized that women who developed diabetes years after pregnancy had experienced abnormally high fetal and neonatal mortality (2). By the 1950s the term "gestational diabetes" was applied to what was thought to be a transient condition that affected fetal outcomes adversely, then abated after delivery (3). In the 1960s, O'Sullivan found that the degree of glucose intolerance during pregnancy was related to the risk of developing diabetes after pregnancy.…”

Section: Historical Perspectivementioning

confidence: 99%

Gestational diabetes mellitus

Buchanan¹,

Xiang²

2005

J. Clin. Invest.

739

408

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Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy. GDM is detected through the screening of pregnant women for clinical risk factors and, among at-risk women, testing for abnormal glucose tolerance that is usually, but not invariably, mild and asymptomatic. GDM appears to result from the same broad spectrum of physiological and genetic abnormalities that characterize diabetes outside of pregnancy. Indeed, women with GDM are at high risk for having or developing diabetes when they are not pregnant. Thus, GDM provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease.

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Section: Historical Perspectivementioning

confidence: 99%

Gestational diabetes mellitus

Buchanan¹,

Xiang²

2005

J. Clin. Invest.

739

408

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“…2 In 1979 the National Diabetes Data Group (NDDG) in the United States recommended that gestational diabetes be recognised as a distinct entity with its own criteria for which all high risk pregnant women should be screened. 3 The following year the American Diabetes Association suggested using a two step procedure: a 50 g glucose challenge test followed, if the result was positive, by an oral glucose tolerance test for all pregnant women (table⇓).…”

Section: Introductionmentioning

confidence: 99%

Gestational diabetes: new criteria may triple the prevalence but effect on outcomes is unclear

Cundy

Ackermann

Ryan

2014

BMJ

138

108

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“…The realization that diabetes could appear in pregnancy and resolve at the end of pregnancy occurred in the late 1800s; although the term 'gestational diabetes' was first coined in 1957 by Carrington [6].…”

Section: History Of the Diagnosis Of Gdmmentioning

confidence: 99%

Suggested consensus for the diagnosis of gestational diabetes

Donaldson¹,

McIntyre²

2014

Diabetes Management

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Recent proposals for the revision of diagnostic criteria for gestational diabetes mellitus (GDM) have engendered worldwide debate. Within and between countries there is disagreement between obstetric, medical and endocrine groups regarding the diagnosis and management of GDM. There have been many articles written recently on this topic in an attempt to clarify opinions and, in some cases, promote a more unified approach. This review aims to discuss the criteria currently in use for the diagnosis of GDM and proposes the universal acceptance of the International Association for Diabetes in Pregnancy Study Group (IADPSG) GDM diagnostic criteria. It also aims to put into perspective the importance of GDM and its increasing prevalence, irrespective of the criteria used for diagnosis. Other factors associated with GDM diagnosis are also covered, including the epidemiology of testing for GDM around the world, the suggested elimination of a two-step diagnostic approach, the cost-effectiveness of testing and the approach to testing in resource-poor settings.There is a continuous relationship between glycemia and adverse pregnancy outcomes.Identifying gestational diabetes mellitus (GDM) provides an opportunity for meaningful health interventions to prevent Type 2 diabetes mellitus and other associated morbidities later in life.Unified criteria will facilitate research into the area of GDM treatment and outcomes.The increased GDM prevalence with new GDM criteria is concordant with the increased prevalence of impaired glucose tolerance in the general population.Testing for GDM is cost effective.The option of using fasting blood glucose alone for GDM diagnosis requires further investigation in different populations/ethnic groups.In resource-poor settings, the use of simplified protocols for testing, including the use of finger-stick glucose measurements, is an area of ongoing investigation.The use of the glucose challenge test and a two-step diagnostic process is not recommended.

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Evaluation of the Prediabetic State During Pregnancy

Cited by 75 publications

References 0 publications

Gestational diabetes mellitus

Gestational diabetes mellitus

Gestational diabetes: new criteria may triple the prevalence but effect on outcomes is unclear

Suggested consensus for the diagnosis of gestational diabetes

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