Evaluation of the Optic Nerve by Strain and Shear Wave Elastography in Patients With Migraine

Abstract

Objectives To investigate the optic nerve's elastic properties using shear wave and strain elastography in patients with migraine compared to healthy individuals. Methods The migraine group consisted of 30 patients (16 with visual auras and 14 without auras) who had previously had a diagnosis of migraine. These were age and sex matched with healthy participants to form the control group. The findings from shear wave and strain elastography in the groups were compared. The elastographic examination was performed with a 6–15‐MHz multifrequency linear array transducer. Results The evaluation involved 30 patients with migraine (3 male and 27 female), whose mean age ± SD was 34.63 ± 10 years, and 30 healthy participants (3 males, 27 females), whose mean age was 36.4 ± 10.5 years. In strain elasticity patterns, a statistically insignificant hardening of the optic nerve in the patients with migraine was observed (P = .052). Analysis of the shear wave elastic modulus values (9.8 ± 3.34 and 12.3 ± 5.25 kPa; P = .03) revealed that differences between the healthy participants and patients with migraine were statistically significant. The results for elasticity patterns and the shear modulus suggested that the differences between migraines with and without visual auras were insignificant (P > .05). A positive correlation was discovered between the duration of the disease and the shear modulus in the patients with migraine (r = 0.496; P < .01). Conclusions Histopathologic changes in the optic nerve may be seen in patients with migraine due to possible fibrotic changes. Elastographic techniques can be useful diagnostic tools for investigating these changes.

Sonoelastographic Evaluation of the Lower Lateral Nasal Cartilage Lateral Crus, Auricular Conchal Cartilage, and Costal Cartilage

“…[7][8][9] Elastography has been successfully applied to lesions of the breast, prostate, pancreas, lymph nodes, thyroid gland, liver, and tendon. [1][2][3][4][5][6] The external shape of the nasal tip is determined by the curves and contours of the lower lateral cartilages. 10 In rhinoplasty operations, cartilage grafts are commonly used.…”

Ocular Ultrasound

“…Doppler ultrasound, both color and spectral, finds use in examining blood flow in the ophthalmic and central retinal arteries and veins as well as vascular malformations. Optic nerve evaluation using elastography also has been described 10 …”

Assessment of the optic nerve, optic disc, and perineural area using shear-wave elastography in patients with multiple sclerosis

“…We standardized the examination technique based on literature. 9,13,14 In addition to the optic nerve, we obtained the measurements of the perineural area and optic disc by SWE. We used the transverse plane from inside the equator of the eyeball and longitudinal axis of the optic nerve for measurements and then saved static images.…”