Evaluation of the Inhalation Toxicity of Diethylethanolamine (DEEA) in Rats

Hinz, John; Thomas, John A.; Ben-Dyke, R.

doi:10.1093/toxsci/18.3.418

Cited by 2 publications

(2 citation statements)

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“…Some exposure-related lesions were observed in the upper respiratory tract at the two highest dose levels, including among other, hyperplasia and inflammatory cell infiltrations. Bronchoconstriction was not measured, so the indication of asthma induction potentials is solely based on the symptoms of irritation (Hinz et al, 1992).…”

Section: -Diethylaminoethanolmentioning

confidence: 99%

Asthma‐inducing potential of 28 substances in spray cleaning products—Assessed by quantitative structure activity relationship (QSAR) testing and literature review

Hadrup

Frederiksen

Wedebye

et al. 2021

J of Applied Toxicology

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Exposure to spray cleaning products constitutes a potential risk for asthma induction.We set out to review whether substances in such products are potential inducers of asthma. We identified 101 spray cleaning products for professional use.Twenty-eight of their chemical substances were selected. We based the selection on (a) positive prediction for respiratory sensitisation in humans based on quantitative

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Section: -Diethylaminoethanolmentioning

confidence: 99%

Asthma‐inducing potential of 28 substances in spray cleaning products—Assessed by quantitative structure activity relationship (QSAR) testing and literature review

Hadrup

Frederiksen

Wedebye

et al. 2021

J of Applied Toxicology

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“…No skin sensitization was induced in guinea pigs [168], and no mutagenicity in Ames tests [143], [169]. Inhalation toxicity is associated with strong local irritation of the nasal region and extreme discomfort of the exposed animals; no pathological changes of inner organs occurred in rats exposed to concentrations of up to 76 ppm (0.37 g/m 3 ) for 14 weeks [170], [171]. Likewise, there were no significant treatment-related findings in rats that received ca.…”

Section: N-alkylund N-arylethanolaminesmentioning

confidence: 99%

Ethanolamines and Propanolamines

Frauenkron¹,

Melder²,

Ruider³

et al. 2001

Ullmann's Encyclopedia of Industrial Chemistry

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The article contains sections titled: 1. Introduction 2. Ethanolamines 2.1. Properties 2.1.1. Physical Properties 2.1.2. Chemical Properties 2.2. Production 2.3. Quality Specifications 2.4. Uses 2.5. Economic Aspects 3. N ‐Alkylated Ethanolamines 3.1. Properties 3.1.1. Physical Properties 3.1.2. Chemical Properties 3.2. Production 3.3. Quality Specifications 3.4. Uses and Economic Aspects 4. Isopropanolamines 4.1. Properties 4.1.1. Physical Properties 4.1.2. Chemical Properties 4.2. Production 4.3. Quality Specifications 4.4. Uses 5. N ‐Alkylated Propanolamines and 3‐Alkoxypropylamines 5.1. Properties 5.1.1. Physical Properties 5.1.2. Chemical Properties 5.2. Production 5.3. Quality Specifications 5.4. Uses and Economic Aspects 6. Storage and Transportation 7. Environmental Protection 8. Toxicology and Occupational Health 8.1. General Aspects 8.2. Ethanolamines 8.3. N ‐Alkyl‐ und N ‐Arylethanolamines 8.4. Propanolamines

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Evaluation of the Inhalation Toxicity of Diethylethanolamine (DEEA) in Rats

Cited by 2 publications

References 0 publications

Asthma‐inducing potential of 28 substances in spray cleaning products—Assessed by quantitative structure activity relationship (QSAR) testing and literature review

Asthma‐inducing potential of 28 substances in spray cleaning products—Assessed by quantitative structure activity relationship (QSAR) testing and literature review

Ethanolamines and Propanolamines

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